CAS 39967-60-7

2,4(1H,3H)-Pyrimidinedione,5-(2-deoxy-b-D-erythro-pentofuranosyl)-

Description:

2,4(1H,3H)-Pyrimidinedione, 5-(2-deoxy-b-D-erythro-pentofuranosyl)-, commonly referred to as a nucleoside analog, is characterized by its structural components that include a pyrimidine ring and a deoxyribose sugar. This compound features a pyrimidinedione moiety, which contributes to its biological activity, particularly in nucleic acid metabolism. The presence of the 2-deoxy-D-ribose sugar enhances its stability and bioavailability, making it relevant in pharmaceutical applications, especially in antiviral and anticancer therapies. The compound typically exhibits low solubility in water, which can influence its pharmacokinetics. Its molecular structure allows for interactions with nucleic acid synthesis pathways, potentially inhibiting viral replication or cancer cell proliferation. Additionally, the compound's CAS number, 39967-60-7, is a unique identifier that facilitates its identification in chemical databases and regulatory documents. Overall, this substance is significant in medicinal chemistry due to its potential therapeutic applications and its role as a building block in nucleic acid analogs.

Formula: C₉H₁₂N₂O₅

Synonyms:

• Deoxypseudouridine

2''-Deoxypseudouridine

CAS: 39967-60-7

Ref: 7W-GN5673

2'-Deoxypseudouridine

CAS: 39967-60-7

2'-Deoxypseudouridine is a nucleotide that is synthesized from the sugar ribose-5-phosphate and uracil. It is used in biological systems to transfer phosphate groups, which are vital to the metabolism of energy. 2'-Deoxypseudouridine also binds to DNA, forming stable complexes with enzymes and other molecules. This nucleotide is often found in oligodeoxynucleotides, which are used as antiviral agents. 2'-Deoxypseudouridine has been shown to have antimicrobial activity against various viruses, including hepatitis B virus (HBV). It has also been tested for its ability to inhibit replication of HIV-1 in vitro. The enzyme glycosylase catalyzes the reaction of 2'-deoxypseudouridine with water, producing an unstable intermediate that spontaneously converts into dUMP and pyrophosphate.

Formula: C₉H₁₂N₂O₅

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 228.21 g/mol

Ref: 3D-ND06413

Deoxypseudouridine

CAS: 39967-60-7

Deoxypseudouridine is a nucleotide analog.

Formula: C₉H₁₂N₂O₅

Color and Shape: Solid

Molecular weight: 228.2

Ref: TM-T13645