CAS 40027-72-3

2-bromo-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide

Description:

2-bromo-N-[(1R,2R)-1,3-dihydroxy-1-(4-nitrophenyl)propan-2-yl]acetamide, with the CAS number 40027-72-3, is a chemical compound characterized by its complex structure, which includes a bromo substituent, an acetamide functional group, and a chiral center derived from a dihydroxypropanol. This compound features a nitrophenyl group, which contributes to its potential reactivity and biological activity. The presence of hydroxyl groups suggests that it may engage in hydrogen bonding, influencing its solubility and interaction with biological systems. The stereochemistry indicated by the (1R,2R) configuration is crucial for its biological activity, as chirality can significantly affect the pharmacodynamics and pharmacokinetics of compounds. Overall, this substance may be of interest in medicinal chemistry and pharmacology, particularly in the development of therapeutic agents, due to its unique structural features and potential biological properties.

Formula: C₁₁H₁₃BrN₂O₅

InChI: InChI=1/C11H13BrN2O5/c12-5-10(16)13-9(6-15)11(17)7-1-3-8(4-2-7)14(18)19/h1-4,9,11,15,17H,5-6H2,(H,13,16)/t9-,11-/m1/s1

SMILES: c1cc(ccc1[C@H]([C@@H](CO)N=C(CBr)O)O)N(=O)=O

Bromamphenicol

CAS: 40027-72-3

Bromamphenicol is an analog of chloramphenicol and is an inhibitor of protein synthesis. It has potent antibacterial activity against a wide range of bacteria, including those that are resistant to other antibiotics. Bromamphenicol has been shown to inhibit the activity of human kinases and may have potential as an anticancer agent. Studies have also demonstrated its ability to induce apoptosis in cancer cells and inhibit tumor growth in mice. Additionally, it has been found to be an effective inhibitor of elastase, which is involved in tissue damage and inflammation. Bromamphenicol is excreted primarily in urine and has been used as a marker for renal function.

Formula: C₁₁H₁₃BrN₂O₅

Purity: Min. 95%

Molecular weight: 333.13 g/mol

Ref: 3D-QBA02772