CAS 4004-95-9

Piperazine, 1-phenyl-, hydrochloride (1:2)

Description:

Piperazine, 1-phenyl-, hydrochloride (1:2) is a chemical compound that belongs to the class of piperazine derivatives. It is characterized by the presence of a piperazine ring, which is a six-membered heterocyclic structure containing two nitrogen atoms. The compound is typically encountered as a hydrochloride salt, which enhances its solubility in water and makes it suitable for various applications. This substance is often used in pharmaceutical formulations and may exhibit biological activity, including potential effects on the central nervous system. Its molecular structure allows for interactions with various receptors, which can be of interest in medicinal chemistry. The compound is generally stable under standard conditions but should be handled with care, as with all chemical substances, to avoid exposure or adverse reactions. Proper storage in a cool, dry place is recommended to maintain its integrity. As with any chemical, safety data sheets should be consulted for handling and disposal guidelines.

Formula: C₁₀H₁₄N₂·2ClH

InChI: InChI=1S/C10H14N2.2ClH/c1-2-4-10(5-3-1)12-8-6-11-7-9-12;;/h1-5,11H,6-9H2;2*1H

InChI key: InChIKey=CUTPTQNQXVVRDB-UHFFFAOYSA-N

SMILES: C1(=CC=CC=C1)N2CCNCC2.Cl

Synonyms:

• 1-Phenylpiperazine HCl
• Piperazine, 1-phenyl-, dihydrochloride
• Piperazine, 1-phenyl-, hydrochloride (1:2)
• 1-Phenylpiperazine dihydrochloride

1-Phenylpiperazine Dihydrochloride

CAS: 4004-95-9

Formula: C₁₀H₁₆Cl₂N₂

Color and Shape: Solid

Molecular weight: 235.1534

Ref: IN-DA003EMR

1-Phenylpiperazine Dihydrochloride

Controlled Product

CAS: 4004-95-9

Stability Hygroscopic
Applications 1-Phenylpiperazine was tested for its activity as a topical glaucoma agent.
References Blevins, W., et al.: J. Bacteriol., 112, 513 (1972), Cohen, M., et al.: J. Pharmacol. Exp. Ther., 223, 110 (1982), Parshikov, I., et al.: Appl. Microbiol. Biotechnol., 56, 474 (2001),

Formula: C₁₀H₁₄N₂·2ClH

Color and Shape: Off-White

Molecular weight: 235.15

Ref: TR-P336040

1-Phenylpiperazine-d4

Controlled Product

CAS: 4004-95-9

Applications Labelled 1-Phenylpiperazine (P336040). A class of entactogenic drugs, with possible side effects like headache, nausea or vomiting, agitation, sedation, sexual dysfunction and cardiac death and ventricular arrhythmia.
References Anderson, H. et al.: Clinical Therapeutics, 34, 113 (2012); Hill, S. & Thomas, S.: Clinical Toxicol., 49, 705 (2011); Leonard, C. et al.: Pharmacoepidem. Dr. S., 20, 903 (2011)

Formula: C₁₀D₄H₁₀N₂

Color and Shape: Neat

Molecular weight: 166.256

Ref: TR-P336042

1-Phenylpiperazine Dihydrochloride

Controlled Product

CAS: 4004-95-9

1-Phenylpiperazine Dihydrochloride is an analytical reagent that is used for wastewater treatment. It is a weak base and has been found to be active in the treatment of infectious diseases, such as malaria, tuberculosis and hepatitis. 1-Phenylpiperazine Dihydrochloride reacts with nitrogen atoms to form piperazine. This reaction solution can be used to determine the phenylpiperazine concentration by measuring the change in pH. The biological properties of 1-phenylpiperazine dihydrochloride have been shown through mammalian cell culture experiments using human serum, lc-ms/ms method, anhydrous sodium titration calorimetry, and carcinoid syndrome models in mice. 1-Phenylpiperazine dihydrochloride binds to dopamine receptors, inhibiting their activity and reducing the release of dopamine from nerve cells.

Formula: C₁₀H₁₆Cl₂N₂

Purity: Min. 95%

Molecular weight: 235.15 g/mol

Ref: 3D-EAA00495