CAS 40054-69-1

Etizolam

Description:

Etizolam is a thienodiazepine derivative, primarily known for its anxiolytic, sedative, and hypnotic properties. It is structurally similar to benzodiazepines but contains a thiophene ring, which contributes to its unique pharmacological profile. Etizolam acts on the central nervous system by enhancing the effects of the neurotransmitter gamma-aminobutyric acid (GABA) at the GABA-A receptor, leading to increased inhibitory neurotransmission. This results in effects such as reduced anxiety, muscle relaxation, and sedation. The substance is often used in the treatment of anxiety disorders and insomnia, although it is not approved for medical use in many countries. Etizolam is typically available in tablet form and can vary in potency. Its use carries risks of dependence, tolerance, and withdrawal symptoms, similar to other psychoactive substances. Additionally, it is important to note that the legal status of etizolam varies by region, with some countries classifying it as a controlled substance due to its potential for abuse.

Formula: C₁₇H₁₅ClN₄S

InChI: InChI=1S/C17H15ClN4S/c1-3-11-8-13-16(12-6-4-5-7-14(12)18)19-9-15-21-20-10(2)22(15)17(13)23-11/h4-8H,3,9H2,1-2H3

InChI key: InChIKey=VMZUTJCNQWMAGF-UHFFFAOYSA-N

SMILES: CC=1N2C3=C(C(=NCC2=NN1)C4=C(Cl)C=CC=C4)C=C(CC)S3

Synonyms:

• 4-(2-chlorophenyl)-2-ethyl-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine
• 4-(o-Chlorophenyl)-2-ethyl-9-methyl-6H-thieno(3,2-f)-s-triazolo(4,3-a)(1,4)diazepine
• 4H-s-Triazolo(3,4-c)thieno(2,3-e)(1,4)-diazepine, 6-(o-chlorophenyl)-8-ethyl-1-methyl-
• 6-(o-Chlorophenyl)-8-ethyl-1-methyl-4H-s-triazolo(3,4-c)thieno(2,3-e)(1,4)-diazepine
• 6-(o-Chlorphenyl)-8-aethyl-1-methyl-4H-s-triazolo(3,4-c)thieno(2,3-e)(1,4)diazepin
• 6-(o-Chlorphenyl)-8-aethyl-1-methyl-4H-s-triazolo(3,4-c)thieno(2,3-e)(1,4)diazepin [German]
• 6H-Thieno(3,2-f)(1,2,4)triazolo(4,3-a)(1,4)diazepine, 4-(2-chlorophenyl)-2-ethyl-9-methyl-
• 8-Ethyl-6-(o-chlorophenyl)-1-methyl-4H-s-triazolo(3,4c)thieno(2,3e)-1,4-diazepine
• Ahr 3219
• Brn 0572740
• Depas
• Etizolam [INN:JAN]
• Etizolamum
• Etizolamum [INN-Latin]
• Unii-A76Xi0Hl37
• Y-7131

Etizolam

Controlled Product

CAS: 40054-69-1

Color and Shape: Neat

Ref: LP-ETZ-1753-10

Etizolam, 1mg/ml in Methanol

Controlled Product

CAS: 40054-69-1

Color and Shape: Single Solution

Ref: LP-ETZ-1753-1LM

Etizolam 1.0 mg/ml in Methanol

Controlled Product

CAS: 40054-69-1

Color and Shape: Single Solution

Ref: 61-AMP1386.00-01

Etizolam 0.1 mg/ml in Methanol

Controlled Product

CAS: 40054-69-1

Color and Shape: Single Solution

Ref: 61-AMP1386.00-02

Etizolam

Controlled Product

CAS: 40054-69-1

Color and Shape: Neat

Ref: 61-FOR1386.00

Etizolam

Controlled Product

CAS: 40054-69-1

Color and Shape: Neat

Ref: 86-MM1386.00

Etizolam (1.0 mg/mL in Methanol)

Controlled Product

CAS: 40054-69-1

Formula: C₁₇H₁₅ClN₄S

Color and Shape: Colourless

Molecular weight: 342.85

Ref: TR-KIT0990

Etizolam

Controlled Product

CAS: 40054-69-1

Applications Etilozam is a a thienodiazepine benzodiazepine derivative, and has amnesic, anxiolytic, anticonvulsant, hypnotic, sedative and skeletal muscle relaxant properties. Etizolam is an anxiolytic related to that of the classic benzodiazepines. Etizolam has effect on monoamine metabolism in brain. Etilozam can be used for the short-term treatment of insomnia, anxiety or panic attacks.
References Fukuda, T., et al.: Jpn. J. Pharmacol., 33, 885 (1983), Lydiard, R., et al.: Clin. Ther., 22, A3 (2000), Sanna, E., et al.: Eur. J. Pharmacol., 519, 31 (2005),

Formula: C₁₇H₁₅ClN₄S

Color and Shape: White To Light Yellow

Molecular weight: 342.85

Ref: TR-E933030