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CAS 400602-35-9

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Amlodipine aspartate

Description:
Amlodipine aspartate is a pharmaceutical compound primarily used in the treatment of hypertension and angina. It is a salt form of amlodipine, a calcium channel blocker that helps to relax blood vessels and improve blood flow. The compound is characterized by its ability to inhibit the influx of calcium ions into vascular smooth muscle and cardiac muscle, leading to vasodilation and reduced blood pressure. Amlodipine aspartate is typically administered orally and is known for its long half-life, allowing for once-daily dosing. The substance is generally well-tolerated, with common side effects including headache, edema, and fatigue. Its solubility and stability are influenced by the aspartate salt form, which can enhance its bioavailability compared to other formulations. As with any medication, it is essential to consider potential drug interactions and contraindications when prescribing amlodipine aspartate. Overall, this compound plays a significant role in cardiovascular therapy, contributing to improved patient outcomes in managing chronic conditions.
Formula:C24H29ClN2O9
InChI:InChI=1S/C24H29ClN2O9/c1-4-36-24(33)21-17(12-35-10-9-26-16(22(30)31)11-18(28)29)27-13(2)19(23(32)34-3)20(21)14-7-5-6-8-15(14)25/h5-8,16,20,26-27H,4,9-12H2,1-3H3,(H,28,29)(H,30,31)
InChI key:InChIKey=OWGHROPUZICLBA-UHFFFAOYSA-N
SMILES:C(OCC)(=O)C=1C(C(C(OC)=O)=C(C)NC1COCCNC(CC(O)=O)C(O)=O)C2=C(Cl)C=CC=C2
Synonyms:
  • L-Aspartate amlodipine
  • Amlodipine aspartate
  • 3,5-Pyridinedicarboxylic acid, 4-(2-chlorophenyl)-2-[[2-[(1,2-dicarboxyethyl)amino]ethoxy]methyl]-1,4-dihydro-6-methyl-, 3-ethyl 5-methyl ester
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