CAS 40069-06-5
:N-hydroxy-3-(trifluoromethyl)benzamide
Description:
N-hydroxy-3-(trifluoromethyl)benzamide is an organic compound characterized by the presence of a hydroxylamine functional group (-NHOH) attached to a benzamide structure, specifically at the meta position relative to a trifluoromethyl group (-CF3). This compound typically exhibits properties associated with both the amide and hydroxylamine functionalities, including potential reactivity in nucleophilic substitution and condensation reactions. The trifluoromethyl group contributes to the compound's lipophilicity and can influence its electronic properties, making it a useful moiety in medicinal chemistry and material science. N-hydroxy-3-(trifluoromethyl)benzamide may also exhibit biological activity, potentially serving as an intermediate in the synthesis of pharmaceuticals or agrochemicals. Its stability, solubility, and reactivity can vary depending on the solvent and conditions used in experiments. As with many chemical substances, safety precautions should be taken when handling this compound, as it may pose health risks or environmental hazards.
Formula:C8H6F3NO2
Synonyms:- N-hydroxy-3-(trifluoromethyl)benzamide
- Benzamide, N-hydroxy-3-(trifluoromethyl)-
Sort by
Purity (%)
0
100
|
0
|
50
|
90
|
95
|
100
Found 1 products.
N-Hydroxy-3-(trifluoromethyl)benzamide
CAS:<p>N-Hydroxymethyl-3-(trifluoromethyl)benzamide is an oxidative and reductive elimination agent that can be used in a variety of synthetic reactions. This compound can be used to synthesize hydroxamic acids, alkenylations, carboxylates, and other functionalized organic compounds. This compound is also useful for the preparation of aromatic carboxylic acid derivatives. The mechanism for this reaction is the hydroxamic acid formation through reductive elimination followed by the addition of an alcohol or amine. The reaction begins with the oxidative cleavage of an ester or amide bond to form a carbonyl group and a hydroxylamine moiety. The hydroxylamine then undergoes reductive elimination to yield a hydroxamic acid. This process is catalyzed by metal ions such as copper (Cu), zinc (Zn), and iron (Fe).</p>Formula:C8H6F3NO2Purity:Min. 95%Molecular weight:205.13 g/mol
