CAS 401-10-5

Retinoyl β-glucuronide

Description:

Retinoyl β-glucuronide, with the CAS number 401-10-5, is a derivative of retinoic acid, which is a metabolite of vitamin A. This compound is characterized by the conjugation of retinoic acid with glucuronic acid, enhancing its solubility and stability. It typically appears as a yellow to orange solid and is known for its role in the metabolism of retinoids in biological systems. Retinoyl β-glucuronide is often studied for its potential biological activities, including its involvement in cellular signaling and regulation of gene expression. It is also of interest in dermatological research due to its implications in skin health and development. The compound is soluble in organic solvents and exhibits a relatively low solubility in water, which is common for many retinoid derivatives. Its stability can be influenced by factors such as pH and light exposure, making proper handling essential in laboratory settings. Overall, Retinoyl β-glucuronide serves as an important compound in both biochemical research and potential therapeutic applications.

Formula: C₂₆H₃₆O₈

InChI: InChI=1S/C26H36O8/c1-15(11-12-18-17(3)10-7-13-26(18,4)5)8-6-9-16(2)14-19(27)33-25-22(30)20(28)21(29)23(34-25)24(31)32/h6,8-9,11-12,14,20-23,25,28-30H,7,10,13H2,1-5H3,(H,31,32)/b9-6+,12-11+,15-8+,16-14+/t20-,21-,22+,23-,25+/m0/s1

InChI key: InChIKey=MTGFYEHKPMOVNE-NEFMKCFNSA-N

SMILES: O(C(/C=C(/C=C/C=C(/C=C/C=1C(C)(C)CCCC1C)\C)\C)=O)[C@@H]2O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]2O

Synonyms:

• 1-O-Retinoyl-.beta.-D-glucopyranuronic acid
• Glucopyranosiduronic acid, 1-retinoate, β-<span class="text-smallcaps">D</span>-
• Retinoic acid, 1-ester with glucopyranuronic acid
• Retinoic acid, 1-ester with β-<span class="text-smallcaps">D</span>-glucopyranosiduronic acid
• Retinoic acid, β-<span class="text-smallcaps">D</span>-glucopyranuronic acid deriv.
• Retinoic acid, β-<span class="text-smallcaps">D</span>-glucuronosyl ester
• Retinoyl β-glucuronide
• all-trans-Retinoyl glucuronide
• all-trans-Retinoyl β-<span class="text-smallcaps">D</span>-glucuronide
• β-<span class="text-smallcaps">D</span>-Glucopyranuronic acid, 1-retinoate
• Retinoic acid, 1-ester with β-D-glucopyranosiduronic acid
• Retinoic acid, β-D-glucopyranuronic acid deriv.
• Glucopyranosiduronic acid, 1-retinoate, β-D-

Tretinoin Glucuronide

CAS: 401-10-5

Formula: C₂₆H₃₆O₈

Molecular weight: 476.57

Ref: 4Z-T-114004

all-trans Retinoyl β-D-Glucuronide

CAS: 401-10-5

all-trans Retinoyl β-D-glucuronide is a metabolite of all-trans retinoic acid formed by the UDP-glucuronosyltransferase (UGT) system.

Formula: C₂₆H₃₆O₈

Color and Shape: Solid

Molecular weight: 476.56

Ref: TM-T35952

E-Retinoyl b-glucuronide

CAS: 401-10-5

Ref: 7W-GC6085

E-Retinoyl b-glucuronide

Controlled Product

CAS: 401-10-5

E-Retinoyl b-glucuronide (ETBG) is a fluorescent derivative of retinoic acid that is used in the detection of chlorogenic acids in human serum. ETBG binds to the Toll-like receptor 4 (TLR4) on human neutrophils, leading to increased cytokine production and chemotaxis. ETBG has been shown to have anti-inflammatory properties and may be useful as an adjuvant for nonsteroidal anti-inflammatory drugs. It has also been shown to inhibit ovarian activity and to have antimicrobial activity against hl-60 cells.

Formula: C₂₆H₃₆O₈

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 476.56 g/mol

Ref: 3D-MR04801

Tretinoin Glucuronide

CAS: 401-10-5

Formula: C₂₆H₃₆O₈

Molecular weight: 476.57

Ref: ST-EA-CP-T101020