CAS 401567-90-6

8-Chloro-4-(1-piperazinyl)-2-(trifluoromethyl)quinoline

Description:

8-Chloro-4-(1-piperazinyl)-2-(trifluoromethyl)quinoline is a chemical compound characterized by its quinoline backbone, which is a bicyclic structure containing a benzene ring fused to a pyridine ring. The presence of a chloro group at the 8-position and a trifluoromethyl group at the 2-position contributes to its unique chemical properties, enhancing its lipophilicity and potential biological activity. The piperazine moiety at the 4-position introduces basic nitrogen atoms, which can participate in hydrogen bonding and influence the compound's interaction with biological targets. This compound is of interest in medicinal chemistry, particularly for its potential pharmacological applications, including antimicrobial and antitumor activities. Its molecular structure suggests that it may exhibit significant interactions with various receptors or enzymes, making it a candidate for further research in drug development. Additionally, the trifluoromethyl group is known to enhance metabolic stability and bioavailability, which are critical factors in the design of effective therapeutic agents.

Formula: C₁₄H₁₃ClF₃N₃

InChI: InChI=1S/C14H13ClF3N3/c15-10-3-1-2-9-11(21-6-4-19-5-7-21)8-12(14(16,17)18)20-13(9)10/h1-3,8,19H,4-7H2

InChI key: InChIKey=GYLMHFWBDILTEA-UHFFFAOYSA-N

SMILES: C(F)(F)(F)C=1C=C(C2=C(N1)C(Cl)=CC=C2)N3CCNCC3

Synonyms:

• Quinoline, 8-chloro-4-(1-piperazinyl)-2-(trifluoromethyl)-
• 1-[8-Chloro-2-(trifluoromethyl)quinol-4-yl]piperazine
• 8-Chloro-4-(1-piperazinyl)-2-(trifluoromethyl)quinoline

1-[8-Chloro-2-(trifluoromethyl)quinol-4-yl]piperazine

CAS: 401567-90-6

1-[8-Chloro-2-(trifluoromethyl)quinol-4-yl]piperazine

Purity: 97%

Molecular weight: 315.72g/mol

Ref: 54-PC8871

8-Chloro-4-piperazin-1-yl-2-(trifluoromethyl)quinoline

CAS: 401567-90-6

Formula: C₁₄H₁₃ClF₃N₃

Molecular weight: 315.72

Ref: 10-F017293