CAS 40172-95-0

1-(2-Furoyl)piperazine

Description:

1-(2-Furoyl)piperazine is an organic compound characterized by its piperazine ring, which is a six-membered cyclic amine, substituted with a furoyl group. The furoyl moiety, derived from furan, contributes to the compound's aromatic properties and potential reactivity. This substance typically appears as a solid or crystalline material and is soluble in various organic solvents, reflecting its polar nature due to the presence of the furoyl carbonyl group. The compound may exhibit biological activity, making it of interest in medicinal chemistry and pharmacology. Its structure allows for potential interactions with biological targets, which can be explored for therapeutic applications. Additionally, the presence of both the piperazine and furoyl groups may influence its pharmacokinetic properties, such as absorption, distribution, metabolism, and excretion. As with many chemical substances, safety and handling precautions should be observed, as it may pose risks depending on concentration and exposure routes. Further studies are often necessary to fully elucidate its properties and potential applications in various fields.

Formula: C₉H₁₂N₂O₂

InChI: InChI=1S/C9H12N2O2/c12-9(8-2-1-7-13-8)11-5-3-10-4-6-11/h1-2,7,10H,3-6H2

InChI key: InChIKey=SADPINFEWFPMEA-UHFFFAOYSA-N

SMILES: C(=O)(C1=CC=CO1)N2CCNCC2

Synonyms:

• 1-(2-Furanoyl)piperazine
• 1-(2-Furanyl)Piperazine
• 1-(2-Furanylcarbonyl)piperazine
• 1-(2-Furylcarbonyl)piperazine
• 1-(Furan-2-carbonyl)piperazine
• 2-Furanyl-1-piperazinylmethanone
• 4-(Furan-2-Ylcarbonyl)Piperazin-1-Ium
• 4-(Furan-2-ylcarbonyl)piperazine
• Furan-2-Yl(Piperazin-1-Yl)Methanone
• Methanone, 2-furanyl-1-piperazinyl-
• N-(2-Furancarbonyl)piperazine
• N-(2-Furoyl)piperazine
• N-(Furan-2-oyl)piperazine
• Piperazine, 1-(2-furanylcarbonyl)-

Prazosin Related Compound D (Furan-2-yl(piperazin-1-yl)methanone)

CAS: 40172-95-0

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₉H₁₂N₂O₂

Color and Shape: Yellow Pale Yellow Crystalline Powder

Molecular weight: 180.08988

Ref: 45-1554749

1-(2-Furoyl)piperazine

CAS: 40172-95-0

Formula: C₉H₁₂N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 180.2038

Ref: IN-DA003CUF

1-(Furan-2-ylcarbonyl)piperazine

Controlled Product

CAS: 40172-95-0

Formula: C₉H₁₂N₂O₂

Color and Shape: Neat

Molecular weight: 180.20

Ref: 86-MM0085.02

1-(2-Furoyl)piperazine

CAS: 40172-95-0

1-(2-Furoyl)piperazine

Formula: C₉H₁₂N₂O₂

Purity: 98%

Color and Shape: light yellow creamy solid

Molecular weight: 180.20378g/mol

Ref: 54-OR6882

Terazosin EP Impurity L (Prazosin EP Impurity D)

CAS: 40172-95-0

Formula: C₉H₁₂N₂O₂

Molecular weight: 180.21

Ref: 4Z-T-7532

Terazosin EP Impurity L

CAS: 40172-95-0

Formula: C₉H₁₂N₂O₂

Molecular weight: 180.21

Ref: ST-EA-CP-T17012

Prazosin EP Impurity D

CAS: 40172-95-0

Formula: C₉H₁₂N₂O₂

Molecular weight: 180.21

Ref: ST-EA-CP-P28004

1-(2-Furoyl)-piperazine

CAS: 40172-95-0

Formula: C₉H₁₂N₂O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 180.207

Ref: 10-F009787

2-Furanyl-1-piperazinylmethanone

Controlled Product

CAS: 40172-95-0

Impurity Terazosin EP Impurity L
Stability Very Hygroscopic
Applications 2-Furanyl-1-piperazinylmethanone (Terazosin EP Impurity L) was utilized in the fragment-based design of symmetrical bis-benzimidazole as inhibitors of R67 dihydrofolate reductase.
References Bastien, D., et al.: J. Med. Chem., 55, 3182 (2012); Giardina, D., et al.: J. Med. Chem., 28, 1354 (1985);

Formula: C₉H₁₂N₂O₂

Color and Shape: Neat

Molecular weight: 180.20

Ref: TR-F864040

1-(2-Furoyl)piperazine

CAS: 40172-95-0

1-(2-Furoyl)piperazine is a potent inhibitor of tyrosinase, an enzyme involved in the production of melanin. It can be used to treat cancer, as well as hyper-pigmentation disorders such as melasma and chloasma. 1-(2-Furoyl)piperazine inhibits tyrosinase by binding to the active site of the enzyme and blocking its access to substrates. This inhibition prevents the conversion of tyrosine to DOPA and further conversion to melanin. 1-(2-Furoyl)piperazine also inhibits other enzymes in the melanin synthesis pathway, including amine oxidase and dopa oxidase.

Formula: C₉H₁₂N₂O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 180.2 g/mol

Ref: 3D-IF36870