CAS 40180-04-9

Tienilic acid

Description:

Tienilic acid, with the CAS number 40180-04-9, is a chemical compound that belongs to the class of sulfonic acids. It is characterized by its sulfonamide functional group, which contributes to its biological activity. Tienilic acid is primarily known for its use as a diuretic and has been studied for its potential therapeutic applications in managing hypertension and edema. The compound is typically a white to off-white crystalline solid, and it is soluble in water, which facilitates its absorption and efficacy in biological systems. Its molecular structure includes a carboxylic acid group, which enhances its acidic properties. Tienilic acid has been investigated for its pharmacological effects, including its ability to inhibit certain enzymes and its interaction with various biological pathways. As with many pharmaceuticals, the safety profile and potential side effects are important considerations in its use. Overall, Tienilic acid exemplifies the intersection of organic chemistry and medicinal applications, showcasing the importance of chemical properties in therapeutic contexts.

Formula: C₁₃H₈Cl₂O₄S

InChI: InChI=1S/C13H8Cl2O4S/c14-11-7(13(18)9-2-1-5-20-9)3-4-8(12(11)15)19-6-10(16)17/h1-5H,6H2,(H,16,17)

InChI key: InChIKey=AGHANLSBXUWXTB-UHFFFAOYSA-N

SMILES: C(=O)(C1=C(Cl)C(Cl)=C(OCC(O)=O)C=C1)C2=CC=CS2

Synonyms:

• 2,3-Dichloro-4-(2-thenoyl)phenoxyacetic acid
• 2-[2,3-Dichloro-4-(2-thienylcarbonyl)phenoxy]acetic acid
• 2-[2,3-Dichloro-4-(thiophene-2-carbonyl)phenoxy]acetic acid
• 4-(2-Thenoyl)-2,3-dichlorophenoxyacetic acid
• 4-(2-Thienylcarbonyl)-2,3-dichlorophenoxyacetic acid
• Acetic Acid, 2-[2,3-Dichloro-4-(2-Thienylcarbonyl)Phenoxy]-
• Acetic Acid, [2,3-Dichloro-4-(2-Thienylcarbonyl)Phenoxy]-
• Anp 3624
• Ce 3624
• Difluorex
• Fr 3068
• Selacryn
• Skf 62698
• Thienylic acid
• Ticrynafen
• Tienylic acid
• [2,3-Dichloro-4-(2-thienylcarbonyl)phenoxy]acetic acid
• [2,3-Dichloro-4-(Thiophen-2-Ylcarbonyl)Phenoxy]Acetic Acid
• {[2,3-Dichloro-4-(2-Thienylcarbonyl)Phenyl]Oxy}Acetic Acid

2-{2,3-dichloro-4-[(thiophen-2-yl)carbonyl]phenoxy}acetic acid

CAS: 40180-04-9

Formula: C₁₃H₈Cl₂O₄S

Purity: 97%

Color and Shape: Solid

Molecular weight: 331.1712

Ref: IN-DA00C0X1

Tienilic Acid

CAS: 40180-04-9

Tienilic Acid

Purity: ≥98%

Molecular weight: 331.17g/mol

Ref: 54-BUP15585

Tienilic acid

CAS: 40180-04-9

Tienilic acid

Purity: 99%

Molecular weight: 331.17g/mol

Ref: 54-OR1026957

Tienilic Acid (Ticrynafen)

CAS: 40180-04-9

Formula: C₁₃H₈Cl₂O₄S

Molecular weight: 331.16

Ref: 4Z-T-403001

Tienilic Acid

CAS: 40180-04-9

Tienilic Acid is a uricosuric diuretic with certain hepatotoxicity

Formula: C₁₃H₈Cl₂O₄S

Purity: 99.55%

Color and Shape: Solid

Molecular weight: 331.17

Ref: TM-T36125

Tienilic Acid

CAS: 40180-04-9

Applications Tienilic Acid is a heterocyclic derivative of phenoxyacetic acid. Tienilic acid is used as diuretic, uricosuric, antihypertensive.
References Kerremans, A.L., et al.: Eur. J. Clin. Pharmacol., 22, 515 (1982), Manier, J.W., et al.: Am. J. Gastroenterol., 77, 401 (1982)

Formula: C₁₃H₈Cl₂O₄S

Color and Shape: White To Light Brown

Molecular weight: 331.17

Ref: TR-T438750

2-(2,3-DICHLORO-4-(THIOPHENE-2-CARBONYL)PHENOXY)ACETIC ACID

CAS: 40180-04-9

Formula: C₁₃H₈Cl₂O₄S

Purity: 97%

Molecular weight: 331.16

Ref: 10-F386465

Tienilic acid

CAS: 40180-04-9

Tienilic acid is a drug that belongs to the group of diastolic pressure-lowering drugs. It lowers blood pressure by inhibiting the renin-angiotensin system, which is a hormone system that regulates blood pressure. Tienilic acid inhibits the activity of renin and angiotensin converting enzyme (ACE), which are enzymes involved in the production of angiotensin II, a peptide that causes vasoconstriction and stimulates the release of aldosterone from the adrenal gland. Tienilic acid has been shown to be safe for use in humans and animals at doses up to 300 mg/kg/day, although it can cause adverse effects such as drug reactions or drug metabolites. Tienilic acid has also been shown to inhibit protease activity in human liver cells, suggesting that it may have an inhibitory effect on other proteases as well.

Formula: C₁₃H₈Cl₂O₄S

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 331.17 g/mol

Ref: 3D-FT28272