CAS 401907-26-4

N-[4-[3-(4-tert-Butylbenzyl)thioureidomethyl]-2-fluorophenyl]methanesulfonamide

Description:

N-[4-[3-(4-tert-Butylbenzyl)thioureidomethyl]-2-fluorophenyl]methanesulfonamide is a chemical compound characterized by its complex structure, which includes a sulfonamide functional group, a thiourea moiety, and a fluorinated aromatic ring. The presence of the tert-butyl group enhances its hydrophobic properties, potentially influencing its solubility and biological activity. The fluorine atom in the aromatic ring can impart unique electronic properties, affecting the compound's reactivity and interaction with biological targets. This compound may exhibit specific pharmacological activities, making it of interest in medicinal chemistry. Its sulfonamide group is known for its role in various therapeutic applications, including antibacterial and antidiabetic agents. The compound's molecular weight, melting point, and solubility characteristics would typically be assessed to understand its physical properties better. Overall, this compound's intricate structure suggests potential utility in drug development, particularly in targeting specific biological pathways or conditions.

Formula: C₂₀H₂₆FN₃O₂S₂

Synonyms:

• Pac-20030
• Sc-0030
• Jyl-1421

JYL 1421

CAS: 401907-26-4

JYL 1421

Purity: ≥98%

Molecular weight: 423.57g/mol

Ref: 54-BUP13965

JYL1421

CAS: 401907-26-4

JYL1421 is a potential drug target for the treatment of chronic cough, inflammatory bowel disease, and diabetic neuropathy. It is an agonist for the TRPV4 receptor. JYL1421 has been shown to increase ATP production in cultured bladder cells and decrease the energy metabolism in cultured cardiac myocytes. It also decreases bowel motility, which may be due to its inhibition of cation channels that are involved in the propagation of nerve impulses. The anti-inflammatory properties of JYL1421 have been demonstrated by its ability to inhibit monocyte chemotactic protein 1 (MCP-1) levels and reduce skin inflammation induced by carrageenan or ultraviolet A radiation.

Formula: C₂₀H₂₆FN₃O₂S₂

Purity: Min. 95%

Molecular weight: 423.57 g/mol

Ref: 3D-BRA90726

JYL 1421

CAS: 401907-26-4

JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM).

Formula: C₂₀H₂₆FN₃O₂S₂

Purity: 98.83%

Color and Shape: Solid

Molecular weight: 423.57

Ref: TM-T15634