CAS 40207-03-2

4-(4-Methoxyphenyl)thiosemicarbazide

Description:

4-(4-Methoxyphenyl)thiosemicarbazide is an organic compound characterized by its thiosemicarbazide functional group, which consists of a thioamide and a hydrazine derivative. This compound features a methoxy group attached to a phenyl ring, contributing to its aromatic properties and influencing its reactivity and solubility. It typically appears as a solid at room temperature and may exhibit moderate solubility in polar organic solvents. The presence of the thiosemicarbazide moiety suggests potential biological activity, as such compounds are often investigated for their pharmacological properties, including antimicrobial and anticancer activities. Additionally, the methoxy group can enhance lipophilicity, potentially affecting the compound's bioavailability. The compound's structure allows for various chemical modifications, making it a versatile building block in medicinal chemistry. Safety data should be consulted for handling, as thiosemicarbazides can pose health risks, including toxicity. Overall, 4-(4-Methoxyphenyl)thiosemicarbazide is of interest in both synthetic and medicinal chemistry contexts.

Formula: C₈H₁₁N₃OS

InChI: InChI=1S/C8H11N3OS/c1-12-7-4-2-6(3-5-7)10-8(13)11-9/h2-5H,9H2,1H3,(H2,10,11,13)

InChI key: InChIKey=XFTUQILJEQYQHK-UHFFFAOYSA-N

SMILES: N(C(NN)=S)C1=CC=C(OC)C=C1

Synonyms:

• 1-Amino-3-(4-methoxyphenyl)thiourea
• 3-Amino-1-(4-methoxyphenyl)thiourea
• 4-(4-Methoxyphenyl)-3-thiosemicarbazide
• 4-(p-Methoxyphenyl)-3-thiosemicarbazide
• 4-(p-Methoxyphenyl)thiosemicarbazide
• Hydrazinecarbothioamide, N-(4-methoxyphenyl)-
• N-(4-Methoxyphenyl)thiosemicarbazide
• N-(4-methoxyphenyl)hydrazinecarbothioamide
• NSC 157324
• Semicarbazide, 4-(p-methoxyphenyl)-3-thio-

4-(4-Methoxyphenyl)-3-thiosemicarbazide

CAS: 40207-03-2

4-(4-Methoxyphenyl)-3-thiosemicarbazide is a carbonyl compound that has been shown to have anticancer activity. It inhibits the growth of cancer cells by binding to the DNA of tumor cells, causing them to undergo apoptosis. 4-(4-Methoxyphenyl)-3-thiosemicarbazide also inhibits influenza virus and bacteria by inhibiting the enzyme ribonucleotide reductase and preventing the synthesis of viral RNA. This agent has potent inhibitory activity against gram-negative species such as Escherichia coli and Pseudomonas aeruginosa.

Formula: C₈H₁₁N₃OS

Purity: Min. 95%

Molecular weight: 197.26 g/mol

Ref: 3D-QBA20703