CAS 4022-81-5

Imidodicarbonimidic diamide, N-(4-chlorophenyl)-, hydrochloride (1:1)

Description:

Imidodicarbonimidic diamide, N-(4-chlorophenyl)-, hydrochloride (1:1), commonly referred to as a derivative of guanidine, is a chemical compound characterized by its imidodicarbonimidic structure, which features two guanidine-like functional groups. This compound is typically encountered as a hydrochloride salt, enhancing its solubility in water and making it suitable for various applications in organic synthesis and medicinal chemistry. The presence of the 4-chlorophenyl group introduces specific electronic and steric properties, which can influence its reactivity and biological activity. As a hydrochloride, it is often more stable and easier to handle compared to its free base form. This compound may exhibit properties such as being a potential intermediate in the synthesis of pharmaceuticals or agrochemicals. Safety data should be consulted, as with any chemical, to understand its toxicity, handling precautions, and environmental impact. Overall, its unique structure and properties make it a subject of interest in both research and industrial applications.

Formula: C₈H₁₀ClN₅·ClH

InChI: InChI=1S/C8H10ClN5.ClH/c9-5-1-3-6(4-2-5)13-8(12)14-7(10)11;/h1-4H,(H6,10,11,12,13,14);1H

InChI key: InChIKey=NAFSLMFLGYXGIF-UHFFFAOYSA-N

SMILES: N(C(NC(=N)N)=N)C1=CC=C(Cl)C=C1.Cl

Synonyms:

• 1-(p-Chlorophenyl)biguanide hydrochloride
• 1-(p-Chlorophenyl)biguanide monohydrochloride
• 2-(4-Chlorophenyl)-1-(Diaminomethylidene)Guanidine Hydrochloride (1:1)
• Biguanide, 1-(p-chlorophenyl)-, monohydrochloride
• Imidodicarbonimidic diamide, N-(4-chlorophenyl)-, hydrochloride (1:1)
• Imidodicarbonimidic diamide, N-(4-chlorophenyl)-, monohydrochloride
• N-(4-Chlorophenyl)imidodicarbonimidic diamide monohydrochloride
• N-(4-chlorophenyl)imidodicarbonimidic diamide
• N-p-Chlorophenylbiguanide hydrochloride
• N-{(1E)-amino[(diaminomethylidene)ammonio]methylidene}-4-chloroanilinium
• [[(4-Chloroanilino)(imino)methyl]amino]methanimidamide hydrochloride

1-(4-Chlorophenyl)biguanide hydrochloride, 97%

CAS: 4022-81-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₁₀ClN₅•HCl

Purity: 97%

Color and Shape: White to pale cream, Crystals or powder or crystalline powder

Molecular weight: 248.12

Ref: 02-B20311

1-(4-Chlorophenyl)biguanide, HCl

CAS: 4022-81-5

Formula: C₈H₁₁Cl₂N₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 248.1124

Ref: IN-DA003CZ0

1-(4-Chlorophenyl)biguanide hydrochloride

CAS: 4022-81-5

1-(4-Chlorophenyl)biguanide hydrochloride

Formula: C₈H₁₀ClN₅·ClH

Purity: ≥95%

Color and Shape: white to off white powder

Molecular weight: 248.11g/mol

Ref: 54-OR1102

1-(4-Chlorophenyl)biguanide Hydrochloride

CAS: 4022-81-5

Color and Shape: Neat

Ref: 86-MM0162.23

1-(4-Chlorophenyl)biguanide Hydrochloride

Controlled Product

CAS: 4022-81-5

Stability Hygroscopic
Applications 1-(4-Chlorophenyl)biguanide is a guanide derivative that can inhibit significantly dihydrofolate reductase (DHFR).
References Baccanari, D., et al.: Biochemistry, 21, 5068 (1982), Ahrweiler, P., et al.: J. Bacteriol., 170, 3301 (1988), Zolli-Juran, M., et al.: Bioorg. Med. Chem. Lett., 13, 2493 (2003),

Formula: C₈H₁₀ClN₅·ClH

Color and Shape: Off-White

Molecular weight: 248.11

Ref: TR-C378540

1-(4-Chlorophenyl)biguanide hydrochloride

CAS: 4022-81-5

Formula: C₈H₁₁Cl₂N₅

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 248.11

Ref: 10-F017146