CAS 402595-29-3

2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(pyridin-4-yl)pyrimidin-4-amine

Description:

The chemical substance known as 2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(pyridin-4-yl)pyrimidin-4-amine, with the CAS number 402595-29-3, is a complex organic compound characterized by its multi-ring structure, which includes a pyrazolo[3,4-b]pyridine and a pyrimidine moiety. This compound features various functional groups, including amines and aromatic rings, contributing to its potential biological activity. It is often studied for its pharmacological properties, particularly in the context of medicinal chemistry, where such compounds may exhibit activity against specific targets in disease pathways. The presence of fluorine in the structure can enhance lipophilicity and metabolic stability, which are important factors in drug design. Additionally, the compound's solubility, stability, and reactivity can be influenced by its structural features, making it a subject of interest in both synthetic and medicinal chemistry research. Overall, this compound exemplifies the complexity and diversity of modern pharmaceutical agents.

Formula: C₂₂H₁₆FN₇

InChI: InChI=1/C22H16FN7/c23-18-6-2-1-4-15(18)13-30-22-16(5-3-9-26-22)19(29-30)21-27-12-17(20(24)28-21)14-7-10-25-11-8-14/h1-12H,13H2,(H2,24,27,28)

Synonyms:

• ETRICIGUAT
• 2-(1-(2-Fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)-5-(pyridin-4-yl)pyrimidin-4-amine
• 4-Pyrimidinamine, 2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-(4-pyridinyl)-

Etriciguat

CAS: 402595-29-3

Etriciguat is a conjugate of guanylate, which is a reactive functional group. It is soluble and degradable, and can be reconstituted in water. Etriciguat stimulates the production of cyclic GMP (cGMP), which has been shown to be effective in treating pulmonary hypertension. Etriciguat has been shown to have diagnostic properties by reacting with a biocompatible fluorescent dye that reacts with cGMP. This reaction causes the emission of light at 615 nm when excited at 340 nm. Etriciguat also has pharmaceutical preparation properties as it can be diluted in an appropriate diluent for intravenous use.

Formula: C₂₂H₁₆FN₇

Purity: Min. 95%

Molecular weight: 397.4 g/mol

Ref: 3D-CRA59529