CAS 4026-18-0

(±)-2-Hydroxyisovaleric acid

Description:

(±)-2-Hydroxyisovaleric acid, with the CAS number 4026-18-0, is an organic compound that belongs to the class of hydroxy acids. It is a chiral molecule, existing as a racemic mixture of two enantiomers. This compound features a hydroxyl group (-OH) and a carboxylic acid group (-COOH) in its structure, which contributes to its acidic properties. It is a colorless to pale yellow liquid or solid, depending on the temperature and purity. The presence of the hydroxyl group allows for hydrogen bonding, which can influence its solubility in water and organic solvents. (±)-2-Hydroxyisovaleric acid is often studied for its potential applications in biochemistry and pharmaceuticals, particularly in metabolic pathways and as a precursor in the synthesis of various compounds. Its biological significance is highlighted in studies related to amino acid metabolism and microbial fermentation processes. Safety data indicates that, like many organic acids, it should be handled with care to avoid irritation or adverse reactions.

Formula: C₅H₁₀O₃

InChI: InChI=1S/C5H10O3/c1-3(2)4(6)5(7)8/h3-4,6H,1-2H3,(H,7,8)

InChI key: InChIKey=NGEWQZIDQIYUNV-UHFFFAOYSA-N

SMILES: C(C(C)C)(C(O)=O)O

Synonyms:

• (2S)-2-hydroxy-3-methylbutanoic acid
• (±)-2-Hydroxyisopentanoic acid
• (±)-2-Hydroxyisovaleric acid
• (±)-α-Hydroxyisovaleric acid
• 2-Hydroxy-3-methylbutanoic acid
• 2-Oxyisovaleric acid
• 3-Methyl-2-hydroxybutyric acid
• <span class="text-smallcaps">DL</span>-2-Hydroxy-3-methylbutanoic acid
• <span class="text-smallcaps">DL</span>-2-Hydroxyisovaleric acid
• <span class="text-smallcaps">DL</span>-α-Hydroxyisovaleric acid
• Butanoic acid, 2-hydroxy-3-methyl-
• Butyric acid, 2-hydroxy-3-methyl-
• NSC 227884
• calcium bis[(2S)-2-hydroxy-3-methylbutanoate]
• dl-2-Hydroxyisovaleric acid

2-Hydroxy-3-methylbutyric acid, 97%

CAS: 4026-18-0

2-Hydroxy-3-methylbutyric acid is employed as internal standard for analysis of ethylene glycol (EG) and -hydroxybutyrate (GHB) in whole blood. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer t

Formula: C₁₀H₁₈CaO₆

Purity: 97%

Color and Shape: White to pale cream, Powder

Molecular weight: 274.33

Ref: 02-H60872

2-Hydroxy-3-methylbutanoic Acid

CAS: 4026-18-0

Formula: C₅H₁₀O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 118.1311

Ref: IN-DA003HE1

2-Hydroxy-3-methylbutanoic acid

CAS: 4026-18-0

2-Hydroxy-3-methylbutanoic acid

Purity: ≥98%

Molecular weight: 118.13g/mol

Ref: 54-BUP13808

2-Hydroxy-3-Methylbutanoic Acid

CAS: 4026-18-0

2-Hydroxy-3-Methylbutanoic Acid

Purity: 97%

Molecular weight: 118.13g/mol

Ref: 54-OR1010470

2-Hydroxy-3-methylbutanoic Acid

CAS: 4026-18-0

Formula: C₅H₁₀O₃

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 118.13

Ref: 3B-H1813

2-Hydroxy-3-Methyl Butyric Acid

CAS: 4026-18-0

Formula: C₅H₁₀O₃

Molecular weight: 118.13

Ref: 4Z-B-086089

2-Hydroxy-3-methylbutanoic acid

CAS: 4026-18-0

2-Hydroxy-3-methylbutanoic acid ((±)-2-Hydroxyisopentanoic Acid) is a metabolite found in the urine of patients with phenylketonuria, methylmalonic acidemia.

Formula: C₅H₁₀O₃

Purity: 98% - 98.63%

Color and Shape: Solid

Molecular weight: 118.13

Ref: TM-T5273

2-Hydroxy-3-methylbutyric Acid

Controlled Product

CAS: 4026-18-0

Applications 2-Hydroxy-3-methylbutyric Acid is a α-hydroxylated butyric acid derivative used as a marker in chemical diagnosis of organic aciduria and other inborn errors. 2-Hydroxy-3-methylbutyric Acid is also used as a metabolomic biomarkers in preeclampsia.
References Nakagawa, K. et al.: J. Chrom. B Anal. Technol. Biomed. Life Sci., 878, 942 (2010); Kenny, L.C. et al.: Reprod. Sci., 15, 591 (2008); Garcia, A. et al.: Clin. Chem., 44, 1905 (1999);

Formula: C₅H₁₀O₃

Color and Shape: Neat

Molecular weight: 118.13

Ref: TR-H946510

2-Hydroxy-3-methylbutyric Acid-d7

Controlled Product

CAS: 4026-18-0

Applications 2-Hydroxy-3-methylbutyric Acid-d7 is the labelled analogue of 2-Hydroxy-3-methylbutyric Acid (H956510), which is a α-hydroxylated butyric acid derivative used as a marker in chemical diagnosis of organic aciduria and other inborn errors. 2-Hydroxy-3-methylbutyric Acid is also used as a metabolomic biomarkers in preeclampsia.
References Nakagawa, K. et al.: J. Chrom. B Anal. Technol. Biomed. Life Sci., 878, 942 (2010); Kenny, L.C. et al.: Reprod. Sci., 15, 591 (2008); Garcia, A. et al.: Clin. Chem., 44, 1905 (1999);

Formula: C₅D₇H₃O₃

Color and Shape: Neat

Molecular weight: 125.174

Ref: TR-H946511

2-Hydroxy-3-methylbutyric acid

CAS: 4026-18-0

2-Hydroxy-3-methylbutyric acid is an intermediate in the microbial metabolism of hydrogen fluoride and caproic acid. It can be used as a diagnostic for probiotic bacteria. 2-Hydroxy-3-methylbutyric acid has been shown to cause cell lysis, which may be due to its ability to act as a polymerase chain reaction (PCR) enhancer. The activity index of 2-hydroxy-3-methylbutyric acid is higher than that of other organic acids, such as 3,4-dimethoxybenzoic acid and ferulic acid.

Formula: C₅H₁₀O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 118.13 g/mol

Ref: 3D-FH09748

2-Hydroxy-3-methylbutanoic acid

CAS: 4026-18-0

Formula: C₅H₁₀O₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 118.132

Ref: 10-F336693

2-Hydroxy-3-methylbutyric Acid-d3

Controlled Product

CAS: 4026-18-0

Formula: C₅D₃H₇O₃

Color and Shape: Neat

Molecular weight: 121.15

Ref: TR-H946512