CAS 402713-81-9

Benzenesulfonamide, N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)-, hydrochloride (1:1)

Description:

Benzenesulfonamide, N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)-, hydrochloride (1:1) is a chemical compound characterized by its sulfonamide structure, which includes a benzenesulfonamide moiety linked to a piperazine ring. This compound features multiple functional groups, including dichloro and methoxy substituents on the aromatic ring, which can influence its biological activity and solubility. The presence of the hydrochloride indicates that it is a salt form, enhancing its stability and solubility in aqueous environments. Typically, compounds of this nature may exhibit pharmacological properties, potentially acting as therapeutic agents in various medical applications. The specific arrangement of substituents can affect the compound's interaction with biological targets, making it of interest in medicinal chemistry. Additionally, the compound's molecular weight, solubility, and other physical properties would be relevant for its application in drug formulation and development. As with all chemical substances, safety data and handling precautions should be considered when working with this compound.

Formula: C₁₈H₂₂Cl₃N₃O₄S

InChI: InChI=1S/C18H21Cl2N3O4S.ClH/c1-26-17-4-3-13(11-16(17)23-7-5-21-6-8-23)28(24,25)22-15-10-12(19)9-14(20)18(15)27-2;/h3-4,9-11,21-22H,5-8H2,1-2H3;1H

InChI key: InChIKey=RNKCEBCFUSXSQE-UHFFFAOYSA-N

SMILES: O(C)C1=C(C=C(S(NC2=C(OC)C(Cl)=CC(Cl)=C2)(=O)=O)C=C1)N3CCNCC3.Cl

Synonyms:

• Benzenesulfonamide, N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)-, hydrochloride (1:1)
• Benzenesulfonamide, N-(3,5-dichloro-2-methoxyphenyl)-4-methoxy-3-(1-piperazinyl)-, monohydrochloride
• SB399885 hydrochloride,SB 399885 hydrochloride

SB 399885 HCl

CAS: 402713-81-9

Formula: C₁₈H₂₂Cl₃N₃O₄S

Purity: 99%

Color and Shape: Solid

Molecular weight: 482.8090

Ref: IN-DA01E4EX

SB 399885 Hydrochloride

Controlled Product

CAS: 402713-81-9

Formula: C₁₈H₂₁Cl₂N₃O₄S•(HCl)

Color and Shape: Neat

Molecular weight: 482.81

Ref: TR-S155008

SB 399885 Hydrochloride

CAS: 402713-81-9

SB 399885 Hydrochloride is a selective 5-HT2A receptor antagonist, which has been shown to reduce food intake and body weight in animal models. SB 399885 Hydrochloride is also a potent and selective 5-HT6 receptor antagonist, with an IC50 of 0.4 nM. SB 399885 Hydrochloride inhibits the activation of the paraventricular nucleus (PVN) neurons by 5-hydroxytryptamine (5-HT) and attenuates the activation of the nucleus accumbens (NAc) neurons by 5-HT. SB 399885 Hydrochloride also blocks the appetitive responses induced by stimulation of the PVN or NAc by 5-HT.

Formula: C₁₈H₂₁Cl₂N₃O₄S•HCl

Purity: Min. 95%

Molecular weight: 446.35 g/mol

Ref: 3D-CRA71381

SB-399885 hydrochloride

CAS: 402713-81-9

SB-399885 hydrochloride is an antagonist of 5-HT6 receptor.

Formula: C₁₈H₂₂Cl₃N₃O₄S

Purity: 98%

Color and Shape: Solid

Molecular weight: 482.81

Ref: TM-T12843