CAS 402849-27-8

4-Chlorobenzoic acid 2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide

Description:

4-Chlorobenzoic acid 2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide is a chemical compound characterized by its complex structure, which includes a hydrazide functional group linked to a chlorobenzoic acid moiety and a methoxy-substituted phenyl group. This compound typically exhibits properties associated with both hydrazides and aromatic compounds, such as moderate solubility in organic solvents and potential reactivity due to the presence of functional groups. The chlorinated aromatic rings may contribute to its biological activity and stability, while the methoxy group can influence its electronic properties and steric hindrance. The presence of the hydrazide linkage suggests potential applications in pharmaceuticals, particularly in the development of anti-inflammatory or antimicrobial agents. Additionally, the compound may exhibit specific melting and boiling points, as well as distinct spectral characteristics in techniques such as NMR and IR spectroscopy, which can be utilized for its identification and characterization in laboratory settings. Overall, this compound represents a unique intersection of functional groups that may be of interest in various chemical and biological research fields.

Formula: C₂₁H₁₆Cl₂N₂O₃

InChI: InChI=1S/C21H16Cl2N2O3/c1-28-19-12-10-18(11-13-19)25(21(27)15-4-8-17(23)9-5-15)24-20(26)14-2-6-16(22)7-3-14/h2-13H,1H3,(H,24,26)

InChI key: InChIKey=GSKPJTLOCASRRI-UHFFFAOYSA-N

SMILES: N(C(=O)C1=CC=C(Cl)C=C1)(NC(=O)C2=CC=C(Cl)C=C2)C3=CC=C(OC)C=C3

Synonyms:

• Benzoic acid, 4-chloro-, 2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide
• 4-Chlorobenzoic acid 2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide
• 4-Chloro-N''-(4-chlorobenzoyl)-N-(4-methoxyphenyl)benzohydrazide
• Indomethacin (Indometacin) EP Impurity F
• Indometacin Impurity 14
• Indometacin EP Impurity F
• Indometacin 1,2-Propylene Glycol Esters (Mixture of Isomers)
• Indomethacin impurity 5/Indomethacin EP Impurity F/2-(4-Chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide-4-chloro-benzoic acid
• Indomethacin EP Impurity F
• Indomethacin Impurity 6(Indomethacin EP Impurity F)
• Indapamide EP Impurity F
• Indometacin (Indomethacin) EP Impurity F
• 4-Chloro-2-(4-chlorobenzoyl)-1-(4-Methoxyphenyl)hydrazide Benzoic Acid

Indomethacin Hydrazine Analog (1-(4-Chlorobenzoyl)-1-(4-methoxyphenyl)-2-(4-chlorobenzoyl)hydrazide)

CAS: 402849-27-8

Aromatic organic derivatives of hydrazine or of hydroxylamine

Formula: C₂₁H₁₆Cl₂N₂O₃

Color and Shape: White Powder

Molecular weight: 414.0538

Ref: 45-1A10010

Indomethacin (Indometacin) EP Impurity F

CAS: 402849-27-8

Formula: C₂₁H₁₆Cl₂N₂O₃

Color and Shape: White To Off-White Solid

Molecular weight: 415.27

Ref: 4Z-I-1216

4-Chloro-2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide Benzoic Acid

CAS: 402849-27-8

Applications An impurity of the anti-inflammatory drug indomnethacin (I641000). Indomethacin inhibits cyclooxygenase (IC50=0.1uM) selectively over liposygenases (IC50=100uM for 5-,12- and 15-LO). A clinically useful NAISD.
References Salari, H., et al.: Prostagland. Leukotrienes Med., 13, 53 (1984), Lehmann, J.M., et al.: J. Biol. Chem., 272, 3406 (1997)

Formula: C₂₁H₁₆Cl₂N₂O₃

Color and Shape: Neat

Molecular weight: 415.27

Ref: TR-C365540

4-Chloro-2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide benzoic acid

CAS: 402849-27-8

4-Chloro-2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide benzoic acid is an activator. It has a CAS number of 402849-27-8 and is available for sale as a research tool. 4-Chloro-2-(4-chlorobenzoyl)-1-(4-methoxyphenyl)hydrazide benzoic acid activates the ligand receptor system by binding to specific receptors, thereby triggering cellular responses such as changes in ion channel activity and protein synthesis. 4CBAB is used in pharmacological research to study the function of ion channels, antibodies, peptides and other cell biology molecules. It can also be used to study protein interactions.

Formula: C₂₁H₁₆Cl₂N₂O₃

Purity: Min. 95%

Molecular weight: 415.3 g/mol

Ref: 3D-CRA84927

Indomethacin EP Impurity F

CAS: 402849-27-8

Formula: C₂₁H₁₆Cl₂N₂O₃

Molecular weight: 415.27

Ref: ST-EA-CP-I7006