CAS 402957-28-2

Telaprevir

Description:

Telaprevir is an antiviral medication primarily used in the treatment of chronic hepatitis C virus (HCV) infection. It belongs to a class of drugs known as protease inhibitors, which work by inhibiting the NS3/4A protease enzyme, crucial for viral replication. Telaprevir is characterized by its chemical formula, which includes elements such as carbon, hydrogen, nitrogen, and oxygen, reflecting its complex organic structure. The substance is typically administered in combination with other antiviral agents to enhance efficacy and reduce the risk of resistance. Telaprevir is known for its relatively high oral bioavailability and is metabolized primarily in the liver, with a half-life that allows for twice-daily dosing. Common side effects may include fatigue, nausea, and rash, among others. Due to its specific mechanism of action and the emergence of newer therapies, the use of telaprevir has evolved, but it remains an important option in the historical context of HCV treatment.

Formula: C₃₆H₅₃N₇O₆

InChI: InChI=1S/C36H53N7O6/c1-5-10-25(29(44)34(48)39-23-15-16-23)40-33(47)28-24-14-9-13-22(24)20-43(28)35(49)30(36(2,3)4)42-32(46)27(21-11-7-6-8-12-21)41-31(45)26-19-37-17-18-38-26/h17-19,21-25,27-28,30H,5-16,20H2,1-4H3,(H,39,48)(H,40,47)(H,41,45)(H,42,46)/t22-,24-,25-,27-,28-,30+/m0/s1

InChI key: InChIKey=BBAWEDCPNXPBQM-GDEBMMAJSA-N

SMILES: C(N[C@H](C(C(NC1CC1)=O)=O)CCC)(=O)[C@@H]2[C@@]3([C@](CN2C([C@@H](NC([C@@H](NC(=O)C=4C=NC=CN4)C5CCCCC5)=O)C(C)(C)C)=O)(CCC3)[H])[H]

Synonyms:

• (1S,3Ar,6As)-2-((S)-2-((S)-2-Cyclohexyl-2-(Pyrazine-6-Carboxamido)Acetamido)-3,3-Dimethylbutanoyl)-N-((S)-1-(Cyclopropylamino)-1,2-Dioxohexan-3-Yl)-Octahydrocyclopenta[C]Pyrrole-1-Carboxamide
• (1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-<span class="text-smallcaps">L</span>-valyl-N-[(1S)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide
• Cyclopenta[c]pyrrole-1-carboxamide, (2S)-2-cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-<span class="text-smallcaps">L</span>-valyl-N-[(1S)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydro-, (1S,3aR,6aS)-
• Cyclopenta[c]pyrrole-1-carboxamide, (2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-<span class="text-smallcaps">L</span>-valyl-N-[(1S)-1-[(cyclopropylamino)oxoacetyl]butyl]octahydro-, (1S,3aR,6aS)-
• Incivek
• Incivo
• Ly 570310
• Mp 424
• S-Telaprevir
• Telaprevir
• Telavic
• Unii-655M5O3W0U
• Vrt 111950
• Vx 950
• (1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1S)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide
• Cyclopenta[c]pyrrole-1-carboxamide, (2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1S)-1-[(cyclopropylamino)oxoacetyl]butyl]octahydro-, (1S,3aR,6aS)-

Telaprevir

CAS: 402957-28-2

Formula: C₃₆H₅₃N₇O₆

Color and Shape: White To Off-White Solid

Molecular weight: 679.87

Ref: 4Z-T-951

Cyclopenta(c)Pyrrole-1-Carboxamide, (2S)-2-Cyclohexyl-N-(Pyrazinylcarbonyl)Glycyl-3-Methyl-L-Valyl-N-((1S)-1-((Cyclopropylamino)Oxoacetyl)Butyl)Octahydro-, (1S,3aR,6aS)-

CAS: 402957-28-2

Cyclopenta(c)Pyrrole-1-Carboxamide, (2S)-2-Cyclohexyl-N-(Pyrazinylcarbonyl)Glycyl-3-Methyl-L-Valyl-N-((1S)-1-((Cyclopropylamino)Oxoacetyl)Butyl)Octahydro-, (1S,3aR,6aS)-

Purity: 98%

Molecular weight: 679.85g/mol

Ref: 54-OR1024393

Telaprevir-d4

CAS: 402957-28-2

Formula: C₃₆H₄₉N₇O₆D₄

Color and Shape: White To Off-White Solid

Molecular weight: 683.89

Ref: 4Z-T-952

Telaprevir

CAS: 402957-28-2

Telaprevir

Purity: ≥95%

Molecular weight: 679.85g/mol

Ref: 54-BUP04270

Telaprevir

CAS: 402957-28-2

Color and Shape: Neat

Ref: 86-MM3379.00

Telaprevir

CAS: 402957-28-2

Formula: C₃₆H₅₃N₇O₆

Purity: ≥ 99.0%

Color and Shape: White to light yellow powder

Molecular weight: 679.85

Ref: 7W-GP5773

Telaprevir

CAS: 402957-28-2

Telaprevir (Incivek) (VX-950) is an effective inhibitor of HCV NS3-4A serine protease (IC50: 0.35 μM).

Formula: C₃₆H₅₃N₇O₆

Purity: 96.9% - 98.89%

Color and Shape: Solid

Molecular weight: 679.85

Ref: TM-T6190

Telaprevir

CAS: 402957-28-2

Inhibitor of hepatitis C viral enzyme NS3-4A serine protease

Formula: C₃₆H₅₃N₇O₆

Purity: Min. 98 Area-%

Molecular weight: 679.85 g/mol

Ref: 3D-FT32861

Telaprevir-d4

Controlled Product

CAS: 402957-28-2

Formula: C₃₆H₄₉D₄N₇O₆

Color and Shape: Neat

Molecular weight: 683.87

Ref: TR-T015652

Telaprevir

Controlled Product

CAS: 402957-28-2

Formula: C₃₆H₅₃N₇O₆

Color and Shape: Neat

Molecular weight: 679.85

Ref: TR-T015650