CAS 402957-28-2: Telaprevir
Description:Telaprevir is an antiviral medication primarily used in the treatment of chronic hepatitis C virus (HCV) infection. It belongs to a class of drugs known as protease inhibitors, which work by inhibiting the NS3/4A protease enzyme, crucial for viral replication. Telaprevir is characterized by its chemical formula, which includes elements such as carbon, hydrogen, nitrogen, and oxygen, reflecting its complex organic structure. The substance is typically administered in combination with other antiviral agents to enhance efficacy and reduce the risk of resistance. Telaprevir is known for its relatively high oral bioavailability and is metabolized primarily in the liver, with a half-life that allows for twice-daily dosing. Common side effects may include fatigue, nausea, and rash, among others. Due to its specific mechanism of action and the emergence of newer therapies, the use of telaprevir has evolved, but it remains an important option in the historical context of HCV treatment.
Formula:C36H53N7O6
InChI:InChI=1S/C36H53N7O6/c1-5-10-25(29(44)34(48)39-23-15-16-23)40-33(47)28-24-14-9-13-22(24)20-43(28)35(49)30(36(2,3)4)42-32(46)27(21-11-7-6-8-12-21)41-31(45)26-19-37-17-18-38-26/h17-19,21-25,27-28,30H,5-16,20H2,1-4H3,(H,39,48)(H,40,47)(H,41,45)(H,42,46)/t22-,24-,25-,27-,28-,30+/m0/s1
InChI key:InChIKey=BBAWEDCPNXPBQM-GDEBMMAJSA-N
SMILES:O=C(NC1CC1)C(=O)C(NC(=O)C2N(C(=O)C(NC(=O)C(NC(=O)C3=NC=CN=C3)C4CCCCC4)C(C)(C)C)CC5CCCC25)CCC
- Synonyms:
- (1S,3Ar,6As)-2-((S)-2-((S)-2-Cyclohexyl-2-(Pyrazine-6-Carboxamido)Acetamido)-3,3-Dimethylbutanoyl)-N-((S)-1-(Cyclopropylamino)-1,2-Dioxohexan-3-Yl)-Octahydrocyclopenta[C]Pyrrole-1-Carboxamide
- (1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-<span class="text-smallcaps">L</span>-valyl-N-[(1S)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide
- Cyclopenta[c]pyrrole-1-carboxamide, (2S)-2-cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-<span class="text-smallcaps">L</span>-valyl-N-[(1S)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydro-, (1S,3aR,6aS)-
- Cyclopenta[c]pyrrole-1-carboxamide, (2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-<span class="text-smallcaps">L</span>-valyl-N-[(1S)-1-[(cyclopropylamino)oxoacetyl]butyl]octahydro-, (1S,3aR,6aS)-
- Incivek
- Incivo
- Ly 570310
- Mp 424
- S-Telaprevir
- Telaprevir
- See more synonyms
- Telavic
- Unii-655M5O3W0U
- Vrt 111950
- Vx 950
- (1S,3aR,6aS)-(2S)-2-Cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1S)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydrocyclopenta[c]pyrrole-1-carboxamide
- Cyclopenta[c]pyrrole-1-carboxamide, (2S)-2-cyclohexyl-N-(pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1S)-1-[(cyclopropylamino)oxoacetyl]butyl]octahydro-, (1S,3aR,6aS)-
- Cyclopenta[c]pyrrole-1-carboxamide, (2S)-2-cyclohexyl-N-(2-pyrazinylcarbonyl)glycyl-3-methyl-L-valyl-N-[(1S)-1-[2-(cyclopropylamino)-2-oxoacetyl]butyl]octahydro-, (1S,3aR,6aS)-
