CAS 40296-46-6

4,6-Dichloro-3-pyridinecarboxylic acid ethyl ester

Description:

4,6-Dichloro-3-pyridinecarboxylic acid ethyl ester, with the CAS number 40296-46-6, is an organic compound characterized by its pyridine ring structure substituted with two chlorine atoms and an ethyl ester functional group. This compound typically appears as a solid or liquid, depending on its specific form and purity. It is known for its potential applications in pharmaceuticals and agrochemicals, often serving as an intermediate in the synthesis of various biologically active compounds. The presence of chlorine atoms enhances its reactivity and may influence its biological activity. The ethyl ester group contributes to its solubility properties, making it more amenable for use in organic synthesis. Additionally, this compound may exhibit specific physical properties such as melting point, boiling point, and solubility in various solvents, which are essential for its practical applications. Safety data should be consulted to understand its handling and potential hazards, as with any chemical substance.

Formula: C₈H₇Cl₂NO₂

InChI: InChI=1/C8H7Cl2NO2/c1-2-13-8(12)5-4-11-7(10)3-6(5)9/h3-4H,2H2,1H3

SMILES: CCOC(=O)c1cnc(cc1Cl)Cl

Synonyms:

• 4,6-Dichloropyridine-3-Carboxylic Acid Ethyl Ester
• 4,6-Dichloronicotinic Acid Ethyl Ester
• Ethyl 4,6-Dichloronicotinate
• 2,4-Dichloro-5-carbethoxypyridine
• 4,6-Dichloronicotinic acid ethyl ester ,97%
• Ethyl 4,6-Dichloropyridine-3-Carboxylate

Ethyl 4,6-dichloronicotinate, 95%

CAS: 40296-46-6

Ethyl 4,6-dichloronicotinate, is used as an important raw material and intermediate used in organic Synthesis, pharmaceuticals, agrochemicals and dyestuff. It is also used as a fine chemical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product po

Formula: C₈H₇Cl₂NO₂

Purity: 95%

Color and Shape: White to off-white, Low-melting solid

Molecular weight: 220.05

Ref: 02-H63092

Ethyl 4,6-dichloronicotinate

CAS: 40296-46-6

Formula: C₈H₇Cl₂NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 220.0527

Ref: IN-DA0034V3

Ethyl 4,6-Dichloronicotinate

CAS: 40296-46-6

Formula: C₈H₇Cl₂NO₂

Purity: >98.0%(GC)

Color and Shape: White to Orange to Green powder to lump

Molecular weight: 220.05

Ref: 3B-E1068

Ethyl 4,6-dichloronicotinate

CAS: 40296-46-6

Ethyl 4,6-dichloronicotinate

Formula: C₈H₇Cl₂NO₂

Purity: 97%

Color and Shape: Powder

Molecular weight: 220.05g/mol

Ref: 54-OR46521

Ethyl 4,6-dichloronicotinate

CAS: 40296-46-6

Formula: C₈H₇Cl₂NO₂

Purity: 95%

Color and Shape: Solid

Molecular weight: 220.05

Ref: 10-F043297

Ethyl 4,6-dichloronicotinate

CAS: 40296-46-6

Ethyl 4,6-dichloronicotinate (EDCN) is a hybrid drug that can be used as a clinical drug for the treatment of cancers. EDCN has been shown to have an antiproliferative effect in hematopoietic cells and tumor cells. It is also able to inhibit tyrosine kinase activity and cellular proliferation by inducing apoptosis. EDCN has been shown to be a potent inhibitor of cancer cell growth in vitro and in vivo, with IC50 values ranging from 1 to 10 μM. This drug is active against leukemia, lymphoma, breast cancer, prostate cancer, colorectal cancer, and other cancers that are sensitive to inhibition by tyrosine kinase inhibitors. EDCN binds reversibly to DNA with high affinity and specificity through hydrogen bonding interactions between the nucleobases on its aromatic ring system and the purine bases on dsDNA. This binding inhibits transcription by blocking access of RNA polymerase II to DNA templates

Formula: C₈H₇Cl₂NO₂

Purity: Min. 95%

Molecular weight: 220.05 g/mol

Ref: 3D-FE33985