CAS 403-43-0

4-Fluorobenzoyl chloride

Description:

4-Fluorobenzoyl chloride, with the CAS number 403-43-0, is an aromatic acyl chloride characterized by the presence of a fluorine atom at the para position relative to the carbonyl group in the benzoyl structure. It is a colorless to pale yellow liquid that is typically used as an intermediate in organic synthesis, particularly in the preparation of pharmaceuticals and agrochemicals. This compound is known for its reactivity due to the presence of the acyl chloride functional group, which can readily undergo nucleophilic substitution reactions. It is also sensitive to moisture and can hydrolyze in the presence of water, releasing hydrochloric acid and forming the corresponding carboxylic acid. 4-Fluorobenzoyl chloride has a distinct odor and should be handled with care, as it is corrosive and can cause irritation to the skin, eyes, and respiratory system. Proper safety precautions, including the use of personal protective equipment, are essential when working with this chemical.

Formula: C₇H₄ClFO

InChI: InChI=1S/C7H4ClFO/c8-7(10)5-1-3-6(9)4-2-5/h1-4H

InChI key: InChIKey=CZKLEJHVLCMVQR-UHFFFAOYSA-N

SMILES: C(Cl)(=O)C1=CC=C(F)C=C1

Synonyms:

• 4-Fluorbenzoylchlorid
• 4-Fluorobenozyl Chloride
• 4-Fluorobenzenecarbonyl chloride
• 4-Fluorobenzoic acid chloride
• 4-Fluorobenzoylchloride
• 6-Fluoropyridine-3-Carboxylic Acid
• Benzoyl chloride, 4-fluoro-
• Benzoyl chloride, p-fluoro
• Chlorure de 4-fluorobenzoyle
• Cloruro De 4-Fluorobenzoilo
• Nsc 88305
• p-Fluorobenzoic acid chloride
• p-Fluorobenzoyl chloride

4-Fluorobenzoyl chloride, 98%

CAS: 403-43-0

It is used in the synthesis of polyphenylene ether and thioether ketones and also in the synthesis fluorinated poly(aryl ether ketone)s containing 1,4-naphthalene moieties. It is also used as a raw material in engineering of plastics. This Thermo Scientific Chemicals brand product was originally par

Formula: C₇H₄ClFO

Purity: 98%

Color and Shape: Clear colorless to pale yellow, Liquid

Molecular weight: 158.56

Ref: 02-A12946

4-Fluorobenzoyl chloride

CAS: 403-43-0

Formula: C₇H₄ClFO

Purity: 98%

Color and Shape: Liquid

Molecular weight: 158.5575

Ref: IN-DA003LF5

Haloperidol Impurity 13

CAS: 403-43-0

Formula: C₇H₄ClFO

Color and Shape: White To Off-White Solid

Molecular weight: 158.56

Ref: 4Z-H-0146

4-Fluorobenzoyl chloride

CAS: 403-43-0

4-Fluorobenzoyl chloride

Formula: C₇H₄ClFO

Purity: 98%

Color and Shape: clear. colourless liquid / fused solid

Molecular weight: 158.56g/mol

Ref: 54-PC3630

4-Fluorobenzoyl chloride

CAS: 403-43-0

Formula: C₇H₄ClFO

Purity: ≥ 98.0%

Color and Shape: Clear, colourless to pale yellow liquid

Molecular weight: 158.56

Ref: 7W-GK3478

4-Fluorobenzoyl Chloride

CAS: 403-43-0

Formula: C₇H₄ClFO

Purity: >97.0%(T)

Color and Shape: Colorless to Light yellow to Light orange clear liquid

Molecular weight: 158.56

Ref: 3B-F0213

4-Fluorobenzoyl chloride

CAS: 403-43-0

Formula: C₇H₄ClFO

Purity: 98.0%

Color and Shape: Liquid

Molecular weight: 158.56

Ref: 10-F001636

4-Fluorobenzoyl chloride

CAS: 403-43-0

4-Fluorobenzoyl chloride

Formula: C₇H₄ClFO

Purity: tech

Color and Shape: clear. colourless liquid

Molecular weight: 158.56g/mol

Ref: 54-PC48430

4-Fluorobenzoyl Chloride

Controlled Product

CAS: 403-43-0

Stability Moisture Sensitive
Applications 4-Fluorobenzoyl Chloride is used in the synthesis of tryphostins which act as inhibitors of EGF receptor and Erb82/neu tyrosine kinases. Also used in the synthesis of 1,2,4-triazole-3-thiones as antidepressant agents.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Gazit, A. et al.: J. Med. Chem., 34, 1896 (1991); Kane, J. et al.: J. Med. Chem.,

Formula: C₇H₄ClFO

Color and Shape: Neat

Molecular weight: 158.56

Ref: TR-F588355

4-Fluorobenzoyl chloride

CAS: 403-43-0

4-Fluorobenzoyl chloride is a chemical compound with the molecular formula of C6H4ClF. It is a colorless, volatile liquid that is soluble in water and most organic solvents. 4-Fluorobenzoyl chloride has been shown to have antimicrobial properties against bacteria such as methicillin resistant Staphylococcus aureus (MRSA). It also has antiinflammatory properties and can be used as an analgesic. The phase transition temperature of 4-fluorobenzoyl chloride is -72 degrees Celsius. The analytical method for this compound involves gas chromatography with mass spectrometry detection (GCMS). The receptor binding affinity of 4-fluorobenzoyl chloride is not known.

Formula: C₇H₄ClFO

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 158.56 g/mol

Ref: 3D-FF64280