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CAS 40336-80-9

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Isopropyl Mycophenolate

Description:
Isopropyl mycophenolate, with the CAS number 40336-80-9, is an immunosuppressive agent primarily used in the prevention of organ transplant rejection and the treatment of autoimmune diseases. It is an ester derivative of mycophenolic acid, which inhibits the enzyme inosine monophosphate dehydrogenase (IMPDH), leading to a reduction in purine synthesis and subsequently affecting lymphocyte proliferation. This mechanism makes it particularly effective in suppressing T and B cell activity. Isopropyl mycophenolate is typically administered orally and is characterized by its moderate solubility in organic solvents and limited solubility in water. The compound is known for its relatively favorable safety profile, although it can cause side effects such as gastrointestinal disturbances and an increased risk of infections due to its immunosuppressive properties. Its pharmacokinetics involve rapid absorption and metabolism, with a half-life that supports once or twice daily dosing. Overall, isopropyl mycophenolate represents a significant therapeutic option in managing conditions requiring immune modulation.
Formula:C20H26O6
Synonyms:
  • 4-Hexenoic acid, 6-(1,3-dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxo-5-isobenzofuranyl)-4-methyl-, 1-methylethyl ester, (4E)-
  • Mycophenolic Acid Impurity 5
  • Isopropyl Mycophenolate
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