CAS 403842-38-6

(2R,3S,5R)-2-[2-hex-1-ynyl-6-(methylamino)purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

Description:

The chemical substance with the name "(2R,3S,5R)-2-[2-hex-1-ynyl-6-(methylamino)purin-9-yl]-5-(hydroxymethyl)tetrahydrofuran-3,4-diol" and CAS number "403842-38-6" is a complex organic compound characterized by its unique structural features. It contains a tetrahydrofuran ring, which is a five-membered cyclic ether, and incorporates multiple functional groups, including a hydroxymethyl group and a purine derivative. The presence of a hex-1-ynyl chain indicates that it has an alkyne functional group, contributing to its reactivity and potential biological activity. The stereochemistry is specified by the (2R,3S,5R) configuration, indicating the spatial arrangement of atoms around the chiral centers, which is crucial for its interaction with biological targets. This compound may exhibit pharmacological properties, potentially acting as a nucleoside analog or influencing cellular pathways due to its purine structure. Its solubility, stability, and reactivity would depend on the specific conditions, such as pH and solvent, making it of interest in medicinal chemistry and drug development.

Formula: C₁₇H₂₃N₅O₄

InChI: InChI=1/C17H23N5O4/c1-3-4-5-6-7-11-20-15(18-2)12-16(21-11)22(9-19-12)17-14(25)13(24)10(8-23)26-17/h9-10,13-14,17,23-25H,3-5,8H2,1-2H3,(H,18,20,21)/t10-,13?,14+,17-/m1/s1

Synonyms:

• 2-(1-HEXYNYL)-N-METHYLADENOSINE
• Adenosine, 2-(1-hexyn-1-yl)-N-methyl-
• HEMADO
• 2-(1-Hexynyl)-N6-methyladenosine

HEMADO

CAS: 403842-38-6

HEMADO is a potent and selective agonist of adenosine A3 receptor (Ki: 1.1 nM at the human A3 subtype).

Formula: C₁₇H₂₃N₅O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 361.4

Ref: TM-T15468