CAS 403848-57-7

Caspase-9 Inhibitor III

CAS: 403848-57-7

Caspase-9 Inhibitor III (Ac-LEHD-cmk) blocks caspase-9, protects against ischemic heart damage.

Formula: C₂₄H₃₅ClN₆O₉

Color and Shape: Solid

Molecular weight: 587.02

Ref: TM-T72281

Ac-Leu-Glu-His-Asp-chloromethylketone

CAS: 403848-57-7

Ac-Leu-Glu-His-Asp-chloromethylketone is a creatine kinase inhibitor that prevents the conversion of ATP to ADP. It inhibits mitochondrial pathways, leading to apoptotic and proapoptotic effects. Ac-Leu-Glu-His-Asp-chloromethylketone also has a kinetic effect on cells, where it causes necrotic cell death. This compound can cause proteolytic activity, which leads to the activation of caspase 9 and matrix metalloproteinases. Ac-Leu-Glu-His-Asp chloromethylketone has been shown to have antiinflammatory properties in cellular assays, as well as an ability to inhibit the synthesis of cellular proteins.

Formula: C₂₄H₃₅ClN₆O₉

Purity: Min. 95%

Molecular weight: 587.02 g/mol

Ref: 3D-FA111088

Ac-Leu-Glu-His-Asp-chloromethylketone

CAS: 403848-57-7

Ac-LEHD-CMK, irreversible inhibitor of caspase-9.

Formula: C₂₄H₃₅ClN₆O₉

Purity: 93.4%

Molecular weight: 587.03

Ref: 01-4029126