CAS 404-24-0

2,2,2-Trifluoro-N-phenylacetamide

Description:

2,2,2-Trifluoro-N-phenylacetamide is an organic compound characterized by its unique trifluoromethyl group and an amide functional group. It features a phenyl ring attached to the nitrogen of the amide, contributing to its aromatic properties. The presence of three fluorine atoms on the carbon adjacent to the amide nitrogen significantly influences its chemical behavior, enhancing its polarity and potentially affecting its solubility in various solvents. This compound is typically a solid at room temperature and may exhibit moderate stability under standard conditions. Its fluorinated structure can impart unique reactivity, making it of interest in various chemical syntheses and applications, particularly in pharmaceuticals and agrochemicals. Additionally, the trifluoromethyl group is known to enhance biological activity and lipophilicity, which can be advantageous in drug design. Safety data should be consulted, as fluorinated compounds can pose specific health and environmental risks. Overall, 2,2,2-Trifluoro-N-phenylacetamide is a notable compound in the realm of organic chemistry due to its distinctive structural features and potential applications.

Formula: C₈H₆F₃NO

InChI: InChI=1S/C8H6F3NO/c9-8(10,11)7(13)12-6-4-2-1-3-5-6/h1-5H,(H,12,13)

InChI key: InChIKey=SAPQIENQEZURNZ-UHFFFAOYSA-N

SMILES: N(C(C(F)(F)F)=O)C1=CC=CC=C1

Synonyms:

• α,α,α-Trifluoroacetanilide
• 2,2,2-Trifluoro-N-phenylacetamide
• Acetamide, 2,2,2-trifluoro-N-phenyl-
• Acetanilide, 2,2,2-trifluoro-
• 2,2,2-Trifluoroacetanilide

2,2,2-Trifluoro-N-phenylacetamide

CAS: 404-24-0

Formula: C₈H₆F₃NO

Purity: 97%

Color and Shape: Solid

Molecular weight: 189.1345

Ref: IN-DA003V2D

N-Phenyltrifluoroacetamide

CAS: 404-24-0

N-Phenyltrifluoroacetamide

Formula: C₈H₆F₃NO

Purity: 97%

Color and Shape: grey solid

Molecular weight: 189.13g/mol

Ref: 54-PC10285

2,2,2-Trifluoro-N-phenylacetamide

CAS: 404-24-0

Formula: C₈H₆F₃NO

Purity: >98.0%(GC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 189.14

Ref: 3B-T3645

2,2,2-Trifluoro-n-phenylacetamide

CAS: 404-24-0

2,2,2-Trifluoro-n-phenylacetamide is a functionalized trifluoroacetic acid. It is inactive and can be used for diagnostic purposes. 2,2,2-Trifluoro-n-phenylacetamide reacts with amines to form the corresponding deuterium isotope labeled amine. The heterocyclic amines that are formed react with diazonium salt to produce an enolate anion that reacts with chloride to form the corresponding carboxylic acid derivative. The proton of the carboxylic acid leaves as a protonated ammonium ion, which is stable in alkaline solutions. Amides have a negative charge on the nitrogen atom due to its electron withdrawing properties.

Formula: C₈H₆F₃NO

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 189.13 g/mol

Ref: 3D-FT105152

2,2,2-Trifluoro-N-phenylacetamide

CAS: 404-24-0

Formula: C₈H₆F₃NO

Purity: 97%

Color and Shape: Solid

Molecular weight: 189.137

Ref: 10-F010745