CAS 405-39-0

N2,N6-Bis[(phenylmethoxy)carbonyl]-L-lysine

Description:

N2,N6-Bis[(phenylmethoxy)carbonyl]-L-lysine, with the CAS number 405-39-0, is a derivative of the amino acid lysine, characterized by the presence of two phenylmethoxycarbonyl groups attached to the nitrogen atoms at the N2 and N6 positions of the lysine backbone. This compound typically exhibits properties associated with amino acids, such as solubility in polar solvents and potential reactivity due to the presence of functional groups. The phenylmethoxycarbonyl moieties enhance its lipophilicity and may influence its biological activity, making it of interest in pharmaceutical applications. The compound can participate in various chemical reactions, including peptide bond formation, and may serve as a building block in the synthesis of more complex molecules. Its structural features suggest potential uses in drug design and development, particularly in the context of targeting specific biological pathways or enhancing the pharmacokinetic properties of therapeutic agents. Overall, N2,N6-Bis[(phenylmethoxy)carbonyl]-L-lysine represents a versatile compound in organic and medicinal chemistry.

Formula: C₂₂H₂₆N₂O₆

InChI: InChI=1S/C22H26N2O6/c25-20(26)19(24-22(28)30-16-18-11-5-2-6-12-18)13-7-8-14-23-21(27)29-15-17-9-3-1-4-10-17/h1-6,9-12,19H,7-8,13-16H2,(H,23,27)(H,24,28)(H,25,26)/t19-/m0/s1

InChI key: InChIKey=BLZXFNUZFTZCFD-IBGZPJMESA-N

SMILES: C(OC(N[C@@H](CCCCNC(OCC1=CC=CC=C1)=O)C(O)=O)=O)C2=CC=CC=C2

Synonyms:

• 124: PN: WO2004099237 PAGE: 36 claimed protein
• <span class="text-smallcaps">L</span>-Lysine, N²,N⁶-bis[(phenylmethoxy)carbonyl]-
• Lysine, N²,N⁶-dicarboxy-, N²,N⁶-dibenzyl ester, <span class="text-smallcaps">L</span>-
• N,N-di-cbz-L-lysine free acid
• N,N′-Bis(benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-lysine
• N,N′-Bis(benzyloxycarbonyl)lysine
• N,N′-Di-Z-<span class="text-smallcaps">L</span>-lysine
• N,N′-Dicarbobenzoxy-<span class="text-smallcaps">L</span>-lysine
• N-a-CBZ-(N-e-CBZ)-L-Lys
• N2,N6-Bis-Cbz-L-lysine
• N2,N6-dibenzyloxycarbonyl-L-lysine
• N²,N⁶-Bis(benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-lysine
• N²,N⁶-Bis[(phenylmethoxy)carbonyl]-<span class="text-smallcaps">L</span>-lysine
• N²,N⁶-Dicarbobenzoxy-<span class="text-smallcaps">L</span>-lysine
• N^α,N^ε-Bis(benzyloxycarbonyl)lysine
• N^α,N^ε-Bis(carbobenzyloxy)-<span class="text-smallcaps">L</span>-lysine
• N^α,N^ω-Bis(benzyloxycarbonyl)-<span class="text-smallcaps">L</span>-lysine
• NSC 88474
• N~2~,N~6~-bis[(benzyloxy)carbonyl]-L-lysine
• Z-Lys(Z)
• Z-Lys(Z)-OH
• Z-Lyz(Z)-OH
• di-N-CBZ-L-Lysine di-N-Carbobenzyloxy-L-lysine
• α,ε-Dicarbobenzoxy-<span class="text-smallcaps">L</span>-lysine
• N,N′-Dicarbobenzoxy-L-lysine
• L-Lysine, N2,N6-bis[(phenylmethoxy)carbonyl]-
• Lysine, N2,N6-dicarboxy-, N2,N6-dibenzyl ester, L-
• N2,N6-Bis[(phenylmethoxy)carbonyl]-L-lysine

Z-Lys(Z)-OH

CAS: 405-39-0

Bachem ID: 4000512.

Formula: C₂₂H₂₆N₂O₆

Purity: 99%

Color and Shape: White

Molecular weight: 414.46

Ref: 01-4000512

Z-LYS(Z)-OH

CAS: 405-39-0

Formula: C₂₂H₂₆N₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 414.4516

Ref: IN-DA00BY3G

Z-Lys(Z)-OH

CAS: 405-39-0

Molecular weight: 414.45

Ref: 7W-GM5256

N,N'-Dibenzyloxycarbonyl-L-lysine

CAS: 405-39-0

N,N'-Dibenzyloxycarbonyl-L-lysine

Purity: 98%

Molecular weight: 414.45g/mol

Ref: 54-OR1014115

Z-Lys(z)-OH

CAS: 405-39-0

Formula: C₂₂H₂₆N₂O₆

Purity: >95.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 414.46

Ref: 3B-B6554

Z-Lys(Z)-OH

CAS: 405-39-0

M06233 - Z-Lys(Z)-OH

Formula: C₂₂H₂₆N₂O₆

Purity: 95%

Color and Shape: Solid

Molecular weight: 414.458

Ref: 10-M06233

N,N'-Bis(benzyloxycarbonyl)-L-lysine

CAS: 405-39-0

Color and Shape: Neat

Ref: 86-MM3626.01

N2,N6-Bis(benzyloxycarbonyl)-L-lysine

Controlled Product

CAS: 405-39-0

Applications Protected L-lysine
References Yang, C., et al.: J. Pharm. Sci., 90, 617 (2001), Yamashita, A., et al.: Bioorg. Med. Chem. Lett., 13, 3345 (2003), Vangapandu, S., et al.: Bioorg. Med. Chem., 12, 239 (2004),

Formula: C₂₂H₂₆N₂O₆

Color and Shape: Neat

Molecular weight: 414.45

Ref: TR-B410905

N2,N6-Bis-cbz-L-lysine

CAS: 405-39-0

N2,N6-Bis-cbz-L-lysine is a synthetic acid transporter that is used to inhibit the transport of lysine across the cell membrane. It is an amide, which can be synthesized from lysine and benzoyl chloride. This compound has been shown to have an inhibitory effect on tumor growth in vitro and in vivo. N2,N6-Bis-cbz-L-lysine is active when targeting acidic environments such as tumors. The carbonyl group of this molecule reacts with the hydroxyl group at C4′ on the ribose ring of nucleosides to form a 1,2 diol moiety. This reaction leads to inhibition of DNA synthesis by preventing RNA polymerase from binding to DNA.

Formula: C₂₂H₂₆N₂O₆

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 414.45 g/mol

Ref: 3D-FB18712