CAS 40505-45-1

6H-Furo[2′,3′:4,5]oxazolo[3,2-a]pyrimidine-2-methanol, 7-fluoro-2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-, hydrochloride (1:1), (2R,3R,3aS,9aR)-

Description:

6H-Furo[2′,3′:4,5]oxazolo[3,2-a]pyrimidine-2-methanol, 7-fluoro-2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-, hydrochloride (1:1), (2R,3R,3aS,9aR)- is a complex organic compound characterized by its unique fused ring structure, which incorporates both furo and oxazolo moieties along with a pyrimidine framework. This compound features a hydroxymethyl group and a fluorine substituent, contributing to its potential biological activity. The presence of the hydrochloride salt form indicates enhanced solubility in aqueous environments, which is often advantageous for pharmacological applications. The stereochemistry, denoted by the (2R,3R,3aS,9aR) configuration, suggests specific spatial arrangements of atoms that can influence the compound's interaction with biological targets. This compound may exhibit properties relevant to medicinal chemistry, particularly in the development of therapeutic agents, due to its structural complexity and functional groups. However, detailed studies would be necessary to elucidate its specific biological activities and potential applications.

Formula: C₉H₁₀FN₃O₄·ClH

InChI: InChI=1S/C9H10FN3O4.ClH/c10-3-1-13-8-6(5(15)4(2-14)16-8)17-9(13)12-7(3)11;/h1,4-6,8,11,14-15H,2H2;1H/t4-,5-,6+,8-;/m1./s1

InChI key: InChIKey=RMCFDHVUFKPQRX-CFHSPSGHSA-N

SMILES: O[C@H]1[C@]2([C@](N3C(O2)=NC(=N)C(F)=C3)(O[C@@H]1CO)[H])[H].Cl

Synonyms:

• 6H-Furo[2′,3′:4,5]oxazolo[3,2-a]pyrimidine-2-methanol, 7-fluoro-2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-, monohydrochloride, (2R,3R,3aS,9aR)-
• 5-F-Anhydro-ara-C hydrochloride
• 6H-Furo[2′,3′:4,5]oxazolo[3,2-a]pyrimidine-2-methanol, 7-fluoro-2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-, hydrochloride (1:1), (2R,3R,3aS,9aR)-
• 6H-Furo[2′,3′:4,5]oxazolo[3,2-a]pyrimidine-2-methanol, 7-fluoro-2,3,3a,9a-tetrahydro-3-hydroxy-6-imino-, monohydrochloride, [2R-(2α,3β,3aβ,9aβ)]-
• NSC 166641

Flurocitabine HCl

CAS: 40505-45-1

Flurocitabine HCl

Purity: ≥98%

Molecular weight: 279.65g/mol

Ref: 54-BUP07922

Flurocitabine HCl

CAS: 40505-45-1

Fluorocitabine HCl, a cytarabine analog, hydrolyzes into ara-FC and ara-FU, showing antitumor effects in leukemia and solid cancers.

Formula: C₉H₁₁ClFN₃O₄

Purity: 99.23% - 99.76%

Color and Shape: Soild

Molecular weight: 279.65

Ref: TM-T27342L