CAS 40522-46-1

2-Heptyl-4-quinolone

Description:

2-Heptyl-4-quinolone, with the CAS number 40522-46-1, is a chemical compound that belongs to the class of quinolones, which are bicyclic compounds containing a quinoline structure. This substance is characterized by its heptyl side chain at the second position and a quinolone moiety at the fourth position. It typically exhibits properties such as being a pale yellow to brownish liquid or solid, depending on its purity and specific conditions. 2-Heptyl-4-quinolone is known for its biological activity, particularly in the context of signaling molecules in certain bacterial species, where it can play a role in quorum sensing. This compound may also exhibit antimicrobial properties, making it of interest in various fields, including microbiology and pharmaceuticals. Its solubility can vary, often being more soluble in organic solvents than in water. As with many quinolone derivatives, it may also display a range of chemical reactivity, which can be leveraged in synthetic applications or further chemical modifications.

Formula: C₁₆H₂₁NO

InChI: InChI=1S/C16H21NO/c1-2-3-4-5-6-9-13-12-16(18)14-10-7-8-11-15(14)17-13/h7-8,10-12H,2-6,9H2,1H3,(H,17,18)

InChI key: InChIKey=UYRHHBXYXSYGHA-UHFFFAOYSA-N

SMILES: O=C1C=2C(NC(CCCCCCC)=C1)=CC=CC2

Synonyms:

• Dihydroakutine
• 2-Heptyl-4(1H)-quinolinone
• Pseudane VII
• 4(1H)-Quinolinone, 2-heptyl-
• 4(1H)-Quinolone, 2-heptyl-
• 2-Heptyl-4-quinolone
• 2-Heptylquinoline-4(1H)-one
• 2-Heptylquinolin-4(1H)-one
• 2-heptyl-1H-quinolin-4-one

4(1H)​-​Quinolinone, 2-​heptyl-

CAS: 40522-46-1

Formula: C₁₆H₂₁NO

Purity: 95%

Color and Shape: Solid

Molecular weight: 243.3440

Ref: IN-DA00CKN3

HHQ

CAS: 40522-46-1

HHQ

Purity: ≥98%

Molecular weight: 243.34g/mol

Ref: 54-BUP02608

HHQ

CAS: 40522-46-1

HHQ (2-heptylquinolin-4(1H)-one) is a PqsR antagonist.

Formula: C₁₆H₂₁NO

Purity: 99.46%

Color and Shape: Solid

Molecular weight: 243.34

Ref: TM-T19713

2-Heptylquinolin-4(1H)-one

CAS: 40522-46-1

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 243.35000610351562

Ref: 10-F215543

2-Heptylquinolin-4(1H)-one

CAS: 40522-46-1

Pseudomonas aeruginosa is a Gram-negative bacterium that has been implicated in many infectious diseases. It is a multidrug resistant organism and can be difficult to treat. The mode of action of 2-heptylquinolin-4(1H)-one (2HQ) is not well understood, but it appears to inhibit the growth of P. aeruginosa by binding to copper ions. 2HQ was shown to exhibit antibacterial activity against wild-type strains of P. aeruginosa as well as mutants with reduced copper resistance. 2HQ also reduces the virulence and biofilm formation of P. aeruginosa cells and inhibits the expression of genes involved in energy metabolism, signal transduction, and chlorogenic acid biosynthesis (an endpoint for quorum sensing).

Formula: C₁₆H₂₁NO

Purity: Min. 95%

Molecular weight: 243.35 g/mol

Ref: 3D-QBA52246