CAS 4053-40-1

Quinoline, 4-methyl-, 1-oxide

Description:

Quinoline, 4-methyl-, 1-oxide, also known as 4-methylquinoline N-oxide, is an organic compound characterized by its quinoline structure, which consists of a fused benzene and pyridine ring. This compound features a methyl group at the 4-position of the quinoline ring and an N-oxide functional group, which is indicative of the oxidation of the nitrogen atom in the pyridine ring. It is typically a pale yellow to brown liquid or solid, depending on its purity and form. The presence of the N-oxide group enhances its reactivity, making it a useful intermediate in organic synthesis and a potential candidate for various applications in pharmaceuticals and agrochemicals. Quinoline derivatives are known for their biological activity, including antimicrobial and antimalarial properties. The compound is soluble in organic solvents and may exhibit moderate toxicity, necessitating careful handling in laboratory settings. Its chemical behavior and interactions are influenced by the electron-withdrawing nature of the N-oxide group, which can affect its reactivity in various chemical reactions.

Formula: C₁₀H₉NO

InChI: InChI=1S/C10H9NO/c1-8-6-7-11(12)10-5-3-2-4-9(8)10/h2-7H,1H3

InChI key: InChIKey=BKKKHCJYHYPKBC-UHFFFAOYSA-N

SMILES: CC=1C2=C(N(=O)=CC1)C=CC=C2

Synonyms:

• 4-Methylquinoline N-oxide
• 4-Methylquinoline 1-oxide
• Quinoline, 4-methyl-, 1-oxide
• Lepidine N-oxide
• Lepidine, 1-oxide

4-Methylquinolin-1-ium-1-olate

CAS: 4053-40-1

4-Methylquinolin-1-ium-1-olate is a chemical compound that contains a quinoline ring, which is composed of six carbons and three nitrogens. The quinoline ring is attached to a methyl group, which is one carbon atom bonded to three hydrogen atoms. 4-Methylquinolin-1-ium-1-olate has been shown to react with alkali metals such as lithium and sodium, forming an ionic salt. This reaction may be due to the formation of a hydrogen bond between the quinoline nitrogen and the metal cation. 4-Methylquinolin-1-ium-1-olate can also undergo alkylation reactions with halogens, such as chlorine or bromine, in trichloroacetic acid, forming a chloromethyl or bromomethyl group on the quinoline ring. The addition of trichloroacetic acid leads to the cleavage of a bond

Formula: C₁₀H₉NO

Purity: Min. 95%

Molecular weight: 159.18 g/mol

Ref: 3D-EAA05340