CAS 40580-83-4

9H-Pyrido[3,4-b]indol-7-ol, 1-methyl-, hydrochloride (1:1)

Description:

9H-Pyrido[3,4-b]indol-7-ol, 1-methyl-, hydrochloride (1:1) is a chemical compound characterized by its complex bicyclic structure, which includes a pyridine and indole moiety. This compound typically appears as a hydrochloride salt, indicating that it is soluble in water and may exhibit different properties compared to its free base form. It is often studied for its potential biological activities, including effects on neurotransmitter systems and possible applications in pharmacology. The presence of the hydroxyl group at the 7-position and the methyl group at the 1-position contributes to its chemical reactivity and interaction with biological targets. As with many indole derivatives, it may exhibit fluorescence and can participate in various chemical reactions, making it of interest in both synthetic and medicinal chemistry. Safety and handling precautions should be observed, as with all chemical substances, due to potential toxicity or reactivity.

Formula: C₁₂H₁₀N₂O·ClH

InChI: InChI=1S/C12H10N2O.ClH/c1-7-12-10(4-5-13-7)9-3-2-8(15)6-11(9)14-12;/h2-6,14-15H,1H3;1H

InChI key: InChIKey=IBINNLDPMFWTTI-UHFFFAOYSA-N

SMILES: CC1=C2C(C=3C(N2)=CC(O)=CC3)=CC=N1.Cl

Synonyms:

• 1-Methyl-9H-pyrido[3,4-b]indol-7-ol hydrochloride monohydrate
• 1-Methyl-Beta-Carbolin-7-Ol Hydrochloride Monohydrate
• 1-methyl-2,9-dihydro-7H-beta-carbolin-7-one hydrochloride hydrate
• 9H-Pyrido[3,4-b]indol-7-ol, 1-methyl-, hydrochloride (1:1)
• 9H-Pyrido[3,4-b]indol-7-ol, 1-methyl-, monohydrochloride
• Harmol hydrochloride
• Harmol hydrochloride dihydrate
• NSC 640470

Harmol HCl

CAS: 40580-83-4

Formula: C₁₂H₁₀N₂O·HCl

Molecular weight: 198.23 36.46

Ref: 4Z-H-104003

Harmol hydrochloride hydrate

CAS: 40580-83-4

Formula: C₁₂H₁₀N₂O·HCl·xH₂O

Purity: ≥ 98% (anhydrous basis)

Color and Shape: White to light-yellow crystalline powder

Molecular weight: 234.68 (anhydrous)

Ref: 7W-GP8204

Harmol hydrochloride monohydrate

CAS: 40580-83-4

Harmol hydrochloride monohydrate is a natural product for research related to life sciences. The catalog number is TN4184 and the CAS number is 40580-83-4.

Formula: C₁₂H₁₁ClN₂O

Purity: 98%

Color and Shape: Solid

Molecular weight: 234.68

Ref: TM-TN4184

Harmol hydrochloride monohydrate

Controlled Product

CAS: 40580-83-4

Harmol hydrochloride monohydrate (HHLM) is an agent that is used for the treatment of lysosomal storage diseases. It is a precursor to the harmol glucuronide, which can be converted back to harmol by β-glucuronidase in the gut. Harmol hydrochloride monohydrate has been shown to activate pluripotent stem cells and autophagy, resulting in increased cell survival. This drug also increases the expression of gangliosides and enhances filtration rates in kidney cells. Harmol hydrochloride monohydrate has also been shown to increase β-glucuronidase activity, leading to a decrease in blood levels of harmine hydrochloride.

Purity: Min. 95%

Ref: 3D-BH175460

Harmol hydrochloride

Controlled Product

CAS: 40580-83-4

Activates caspase-8; induces apoptosis

Formula: C₁₂H₁₀N₂O•HCl

Purity: Min. 95%

Molecular weight: 234.68 g/mol

Ref: 3D-FH65039

Harmol hydrochloride monohydrate

Controlled Product

CAS: 40580-83-4

Harmol hydrochloride monohydrate is a β-glucuronidase inhibitor that has been shown to induce autophagy in various cell types. Harmol hydrochloride monohydrate is used to determine the function of lysosomal enzymes, which degrade cellular debris and pathogens. It is also used to examine the effects of harmol glucuronide on pluripotent stem cells. Harmol hydrochloride monohydrate can be injected into mice for fluorescence studies or tritiated for injection solution studies. Harmol hydrochloride monohydrate also has ganglioside activity and can be used as a substrate for harmine hydrochloride in order to produce radioactive harmol.

Formula: C₁₂H₁₃ClN₂O₂

Purity: Min. 98.0 Area-%

Molecular weight: 252.70 g/mol

Ref: 3D-H-1312

Harmol Hydrochloride

Controlled Product

CAS: 40580-83-4

Formula: C₁₂H₁₀N₂O·ClH

Color and Shape: Neat

Molecular weight: 234.681

Ref: TR-H105263

Harmol HCl

CAS: 40580-83-4

Formula: C₁₂H₁₀N₂O·HCl

Color and Shape: Pale Yellow To Off-White Solid

Molecular weight: 198.23 36.46

Ref: 4Z-H-151