CAS 405911-17-3

2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid hydrochloride

Description:

2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid hydrochloride, with CAS number 405911-17-3, is a synthetic organic compound characterized by its complex structure, which includes a chloro-substituted benzyl moiety and a trifluoromethyl group. This compound is typically classified as a pharmaceutical agent, potentially exhibiting properties relevant to therapeutic applications. Its hydrochloride salt form enhances solubility in aqueous environments, making it suitable for various formulations. The presence of multiple aromatic rings and functional groups suggests potential interactions with biological targets, which may contribute to its pharmacological effects. Additionally, the trifluoromethyl group is known to influence lipophilicity and metabolic stability, which are critical factors in drug design. As with many compounds of this nature, safety and efficacy profiles would need to be established through rigorous testing, including in vitro and in vivo studies, to determine its suitability for clinical use.

Formula: C₃₃H₃₂Cl₂F₃NO₃

Synonyms:

• 2-[3-[3-[[2-Chloro-3-(Trifluoromethyl)Phenyl]Methyl-(2,2-Diphenylethyl)Amino]Propoxy]Phenyl]Acetic Acid,Hydrochloride
• GW3965 hydrochloride
• [3-(3-{[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino}propoxy)phenyl]acetic acid hydrochloride (1:1)
• Benzeneacetic acid, 3-[3-[[[2-chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]-, hydrochloride (1:1)

2-[3-[3-[[2-Chloro-3-(trifluoromethyl)benzyl](2,2-diphenylethyl)amino]propoxy]phenyl]acetic acid hydrochloride

CAS: 405911-17-3

Formula: C₃₃H₃₂Cl₂F₃NO₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 618.5133

Ref: IN-DA003QTS

GW3965 hydrochloride

CAS: 405911-17-3

GW3965 hydrochloride

Purity: ≥98%

Molecular weight: 618.51g/mol

Ref: 54-BUP13070

2-[3-[3-[[2-Chloro-3-(Trifluoromethyl) Benzyl](2,2-Diphenylethyl)Amino]Propoxy]Phenyl] Acetic Acid Hydrochloride

CAS: 405911-17-3

2-[3-[3-[[2-Chloro-3-(Trifluoromethyl) Benzyl](2,2-Diphenylethyl)Amino]Propoxy]Phenyl] Acetic Acid Hydrochloride

Purity: 98%

Molecular weight: 618.51g/mol

Ref: 54-PC108907

GW3965 hydrochloride

CAS: 405911-17-3

Formula: C₃₃H₃₁F₃ClNO₃·HCl

Molecular weight: 618.51

Ref: 7W-GL6745

GW3965 Hydrochloride

CAS: 405911-17-3

Formula: C₃₃H₃₁ClF₃NO₃·HCl

Purity: >97.0%(HPLC)(qNMR)

Color and Shape: Colorless to Light yellow clear liquid

Molecular weight: 618.52

Ref: 3B-G0655

GW3965 HCl

CAS: 405911-17-3

Formula: C₃₃H₃₁ClF₃NO₃·HCl

Color and Shape: Pale Brown Solid

Molecular weight: 582.06 36.46

Ref: 4Z-K-031052

GW3965 hydrochloride

CAS: 405911-17-3

GW3965 hydrochloride (GW3965 HCl) is an effective and specific LXR agonist for hLXRα/β (EC50: 190/30 nM).

Formula: C₃₃H₃₁ClF₃NO₃·HCl

Purity: 98.9% - 99.51%

Color and Shape: Solid

Molecular weight: 618.51

Ref: TM-T6310

GW 3965 Hydrochloride

Controlled Product

CAS: 405911-17-3

Applications GW3965 Hydrochloride, is a potent, selective liver X receptor (LXR) agonist for hLXRα and hLXR. GW3965 has shown potent anti-inflammatory activity in both irritant and allergic contact models of dermatitis, requiring the participation of both LXRα and LXRβ.
References Fowler, A.J., et. al.: J. Invest. Dermatol., 120, 246 (2003)

Formula: C₃₃H₃₁ClF₃NO₃•HCl

Color and Shape: Neat

Molecular weight: 582.053646

Ref: TR-G930985

GW 3965 hydrochloride

CAS: 405911-17-3

GW 3965 hydrochloride is a selective liver X receptor (LXR) agonist, which is a synthetic compound derived through pharmaceutical research aimed at modulating lipid metabolism. It functions by binding to and activating LXRs, which are nuclear receptors that regulate the expression of genes involved in cholesterol, fatty acid, and glucose homeostasis. Upon activation, these receptors influence the transcription of various target genes, leading to increased cholesterol efflux, decreased intestinal cholesterol absorption, and modulation of inflammatory responses.

Formula: C₃₃H₃₁ClF₃NO₃•HCl

Purity: Min. 95%

Molecular weight: 618.51 g/mol

Ref: 3D-FG103816