CAS 40615-39-2: 5′-O-(4,4′-Dimethoxytrityl)thymidine

Description: 5′-O-(4,4′-Dimethoxytrityl)thymidine is a modified nucleoside that plays a significant role in the field of molecular biology, particularly in the synthesis of oligonucleotides. This compound features a thymidine base, which is one of the four nucleobases in DNA, and is modified at the 5′ position with a dimethoxytrityl (DMT) protecting group. The DMT group is commonly used in solid-phase DNA synthesis as it provides a means to protect the hydroxyl group during the synthesis process, allowing for the sequential addition of nucleotides. The presence of two methoxy groups in the DMT moiety enhances the stability and solubility of the compound. In terms of its physical properties, 5′-O-(4,4′-Dimethoxytrityl)thymidine is typically a white to off-white solid, and it is soluble in organic solvents such as dichloromethane and methanol. Its chemical structure allows for specific reactivity, making it a valuable intermediate in the production of synthetic DNA and RNA sequences.

Formula: C₃₁H₃₂N₂O₇

InChI: InChI=1S/C31H32N2O7/c1-20-18-33(30(36)32-29(20)35)28-17-26(34)27(40-28)19-39-31(21-7-5-4-6-8-21,22-9-13-24(37-2)14-10-22)23-11-15-25(38-3)16-12-23/h4-16,18,26-28,34H,17,19H2,1-3H3,(H,32,35,36)/t26-,27+,28+/m0/s1

InChI key: InChIKey=UBTJZUKVKGZHAD-UPRLRBBYSA-N

SMILES: O=C1NC(=O)N(C=C1C)C2OC(COC(C=3C=CC=CC3)(C4=CC=C(OC)C=C4)C5=CC=C(OC)C=C5)C(O)C2

Synonyms:

• 1-{(3xi)-5-O-[bis(4-methoxyphenyl)(phenyl)methyl]-2-deoxy-beta-D-glycero-pentofuranosyl}-5-methylpyrimidine-2,4(1H,3H)-dione
• 5'-Dimethoxytrityl Thymidine
• 5'-O-(4,4'-Dimethoxytrityl)-2'-Deoxythymidine
• 5'-O-(4,4'-Dimethoxytrityl)Thymidine
• 5'-O-(Dimethoxytrityl)-Thymidine
• 5'-O-Dimethoxytrityl-Deoxythymidine
• 5'-O-[Bis(4-methoxyphenyl)benzyl]-2'-deoxythymidine
• 5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]thymidine
• 5’-O-[Bis(4-Methoxyphenyl)Phenylmethyl]-Thymidin
• 5′-O-(Di-p-methoxytrityl)thymidine
• 5′-O-(p,p′-Dimethoxytrityl)thymidine
• 5′-O-[Bis(4-methoxyphenyl)phenylmethyl]thymidine
• DMT-dT
• Thymidine, 5′-O-[bis(4-methoxyphenyl)phenylmethyl]-
• Thymidine, 5′-O-[α,α-bis(p-methoxyphenyl)benzyl]-

5'-O-(4,4'-Dimethoxytrityl)thymidine

CAS: 40615-39-2

• Formula: C₃₁H₃₂N₂O₇
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 544.60

5'-O-(4,4'-Dimethoxytrityl)thymidine, 98+%

CAS: 40615-39-2

5'-O-(4,4'-Dimethoxytrityl)thymidine is used in the solid-phase synthesis of polynucleotides and polythymidylic acids by the block …

• Formula: C₃₁H₃₂N₂O₇
• Purity: 98+%
• Color and Shape: White to pale cream, Powder or crystalline powder or crystals
• Molecular weight: 544.60

Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-

CAS: 40615-39-2

• Formula: C₃₁H₃₂N₂O₇
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 544.595

5''-O-(4,4''-Dimethoxytrityl)thymidine (DMT-T)

CAS: 40615-39-2

• Formula: C₃₁H₃₂N₂O₇
• Molecular weight: 544.60

5-O-(4,4-Dimethoxytrityl)thymidine

CAS: 40615-39-2

• Formula: C₃₁H₃₂N₂O₇
• Purity: 98+%
• Color and Shape: white powder
• Molecular weight: 544.59g/mol

5'-O-DMT-dT

CAS: 40615-39-2

5'-O-DMT-dT (5'-O-(4,4'-Dimethoxytrityl)thymidine) is a nucleoside derivative that finds utility in oligonucleotide synthesis.

• Formula: C₃₁H₃₂N₂O₇
• Color and Shape: White Powder
• Molecular weight: 544.59

5’-O-(4,4’-Dimethoxytrityl)thymidine

CAS: 40615-39-2

Applications 5’-O-(4,4’-Dimethoxytrityl)thymidine (cas# 40615-39-2) is a compound useful in organic synthesis.

• Formula: C₃₁H₃₂N₂O₇
• Color and Shape: White To Off-White
• Molecular weight: 544.60

Dmt-t

CAS: 40615-39-2

• Purity: 95.0%
• Color and Shape: Solid
• Molecular weight: 544.60400390625

5'-O-DMT-thymidine

CAS: 40615-39-2

5’-O-DMT-thymidine is also known as 5’-O-(4,4’-dimethoxytrityl)thymidine. It is a key deoxynucleoside building block that is …

• Formula: C₃₁H₃₂N₂O₇
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 544.6 g/mol