CAS 40627-30-3

[(2S,5R)-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-2-yl]methanol

Description:

The chemical substance with the name "[(2S,5R)-5-(4-amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)tetrahydrofuran-2-yl]methanol" and CAS number "40627-30-3" is characterized by its complex molecular structure, which includes a tetrahydrofuran ring and a pyrrolo[2,3-d]pyrimidine moiety. This compound features specific stereochemistry, indicated by the (2S,5R) configuration, which plays a crucial role in its biological activity and interaction with biological targets. The presence of an amino group suggests potential for hydrogen bonding and interaction with various biological systems, making it of interest in medicinal chemistry. Its methanol functional group may enhance solubility and reactivity. The compound's unique structural features may contribute to its pharmacological properties, potentially influencing its efficacy and safety profile in therapeutic applications. Overall, this substance exemplifies the intricate relationship between molecular structure and biological function, highlighting its relevance in drug discovery and development.

Formula: C₁₁H₁₄N₄O₂

InChI: InChI=1/C11H14N4O2/c12-10-8-3-4-15(11(8)14-6-13-10)9-2-1-7(5-16)17-9/h3-4,6-7,9,16H,1-2,5H2,(H2,12,13,14)/t7-,9+/m0/s1

2',3'-Dideoxy   tubercidin

CAS: 40627-30-3

Nucleoside Derivatives - 7-Deaza-purine nucleosides; 2’,3’-Dideoxy nucleosides

Formula: C₁₁H₁₄N₄O₂

Color and Shape: Solid

Molecular weight: 234.25

Ref: TM-TNU1258

7-Deaza-2',3'-dideoxyadenosine

CAS: 40627-30-3

7-Deaza-2',3'-dideoxyadenosine (7DDAD) is a nucleoside analogue that has been used as an immunodeficiency agent. This drug inhibits the replication of the human immunodeficiency virus (HIV). 7DDAD is a prodrug that is converted to adenosine after it enters the cell, and this conversion prevents DNA synthesis. The effective dose of 7DDAD is 50 mg/kg in rats, but this dose may vary depending on the technique used. 7DDAD has been shown to be effective in vitro against HIV-1 and HIV-2 isolates, and it can also be used to treat cytomegalovirus infections. In addition, 7DDAD has been shown to inhibit the growth of various types of cancer cells in vitro.

Formula: C₁₁H₁₄N₄O₂

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 234.26 g/mol

Ref: 3D-ND00041