CAS 40666-16-8
:Fluprostenol
Description:
Fluprostenol is a synthetic prostaglandin analog, specifically a potent agonist of the prostaglandin F2α receptor. It is primarily used in veterinary medicine, particularly for its ability to induce luteolysis in animals, which can help manage reproductive cycles. The compound is characterized by its ability to mimic the natural effects of prostaglandins, leading to smooth muscle contraction and vasodilation. Fluprostenol is typically administered via injection and is known for its relatively rapid onset of action. Its chemical structure includes a carboxylic acid group, which is essential for its biological activity. As with many prostaglandin analogs, it may have side effects, including gastrointestinal disturbances and cardiovascular effects, depending on the dosage and the species being treated. Safety and handling precautions are necessary due to its potent biological activity. Overall, Fluprostenol serves as an important tool in reproductive management in veterinary practices.
Formula:C23H29F3O6
InChI:InChI=1/C23H29F3O6/c24-23(25,26)15-6-5-7-17(12-15)32-14-16(27)10-11-19-18(20(28)13-21(19)29)8-3-1-2-4-9-22(30)31/h1,3,5-7,10-12,16,18-21,27-29H,2,4,8-9,13-14H2,(H,30,31)/t16-,18-,19-,20+,21-/m1/s1
InChI key:InChIKey=WWSWYXNVCBLWNZ-UXOZKJFPNA-N
SMILES:C(=C/[C@@H](COC1=CC(C(F)(F)F)=CC=C1)O)\[C@H]2[C@H](C/C=C\CCCC(O)=O)[C@H](O)C[C@@H]2O
Synonyms:- (5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-{(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl]hept-5-enoic acid
- (5Z)-7-[(1S,2S,3S,5R)-3,5-dihydroxy-2-{(1E,3S)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl]hept-5-enoic acid
- 255-029-3
- 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-, (5Z)-rel-
- 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-, (5Z)-rel-
- 5-Heptenoic acid, 7-[3,5-dihydroxy-2-[3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-, [1α(Z),2β(1E,3R*),3α,5α]-
- 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-{(3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]but-1-en-1-yl}cyclopentyl]hept-5-enoic acid
- Equimate
- Fluoprostenol
- rel-(5Z)-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-buten-1-yl]cyclopentyl]-5-heptenoic acid
- (±)-16-(3-trifluoromethylphenoxy)tetranorprostaglandin f2α
- Travoprost Impurity 31((±)-Fluprostenol)
- (+/-)16-(M-TRIFLUOROMETHYLPHENOXY)-TETRANOR-PROSTAGLANDIN F2ALPHA
- FLUPROSTENOL, ETHANOL SOLUTION
- (+/-)-16-(3-TRIFLUOROMETHYLPHENOXY)TETRANORPROSTAGLANDIN F2ALPHA
- (5Z)-rel-7-[(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(1E,3R)-3-hydroxy-4-[3-(trifluoromethyl)phenoxy]-1-butenyl]cyclopentyl]-5-heptenoic acid
- (+/-)-9ALPHA,11ALPHA,15R-TRIHYDROXY-16-(3-(TRIFLUOROMETHYL)PHENOXY)-17,18,19, 20-TETRANORPROSTA 5Z,13E-DIEN-1-OIC ACID
- WWSWYXNVCBLWNZ-QIZQQNKQSA-N
- See more synonyms
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Found 3 products.
Fluprostenol
CAS:<p>Fluprostenol is a prostaglandin that binds to the nuclear receptor PPAR-α, which regulates lipid and glucose metabolism. Fluprostenol also inhibits the production of leukemia inhibitory factor in 3T3-L1 preadipocytes. It has been shown to possess antimicrobial activity against gram-negative bacteria and eye disorders. Fluprostenol has chemical stability, with a half-life of about 2 hours in human serum, which makes it suitable for use as an ophthalmic preparation. Fluprostenol has properties that are similar to other prostaglandins, such as low potency and pharmacokinetic properties. The LC-MS/MS method is used to measure fluprostenol concentrations in plasma. This method can be used for sample preparation with low potency compounds because it separates compounds based on molecular weight and not polarity or solubility.</p>Purity:Min. 95%


