CAS 4068-75-1

Methyl 5-iodosalicylate

Description:

Methyl 5-iodosalicylate is an organic compound characterized by its aromatic structure, which includes a salicylic acid derivative with a methyl ester functional group and an iodine atom at the 5-position of the aromatic ring. This compound typically appears as a colorless to pale yellow liquid with a sweet, floral odor. It is soluble in organic solvents such as ethanol and ether but has limited solubility in water due to its hydrophobic methyl ester group. Methyl 5-iodosalicylate is known for its applications in organic synthesis, particularly as a reagent in the preparation of various pharmaceuticals and agrochemicals. The presence of the iodine atom enhances its reactivity, making it useful in nucleophilic substitution reactions. Additionally, it exhibits potential biological activities, which may include antimicrobial properties. As with many halogenated compounds, proper handling and safety precautions are essential due to potential toxicity and environmental concerns associated with iodine-containing substances.

Formula: C₈H₇IO₃

InChI: InChI=1S/C8H7IO3/c1-12-8(11)6-4-5(9)2-3-7(6)10/h2-4,10H,1H3

InChI key: InChIKey=NRSWJTRJHPRZMH-UHFFFAOYSA-N

SMILES: C(OC)(=O)C1=C(O)C=CC(I)=C1

Synonyms:

• 2-Hydroxy-5-iodobenzoic acid methyl ester
• 3-Methoxycarbonyl-4-iodophenol
• 5-Iodo-2-hydroxybenzoic acid methyl ester
• 5-Iodosalicylic acid methyl ester
• Benzoic acid, 2-hydroxy-5-iodo-, methyl ester
• Methyl 2-Hydroxy-5-Iodobenzoate
• Methyl 5-iodo-2-hydroxybenzoate
• NSC 66548
• Salicylic acid, 5-iodo-, methyl ester
• Methyl 5-iodosalicylate

Methyl 5-Iodosalicylate

CAS: 4068-75-1

Formula: C₈H₇IO₃

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 278.05

Ref: 3B-I0539

Methyl 5-iodosalicylate, 99%

CAS: 4068-75-1

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₇IO₃

Purity: 99%

Color and Shape: Crystals or powder or crystalline powder, White

Molecular weight: 278.05

Ref: 02-B22048

Methyl 2-hydroxy-5-iodobenzoate

CAS: 4068-75-1

Formula: C₈H₇IO₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 278.0439

Ref: IN-DA003RXY

Methyl 2-hydroxy-5-iodobenzoate

CAS: 4068-75-1

Methyl 2-hydroxy-5-iodobenzoate

Purity: 97%

Molecular weight: 278.04g/mol

Ref: 54-OR14411

Methyl 5-iodosalicylate

CAS: 4068-75-1

Methyl 5-iodosalicylate is an amide compound that has been found to be effective in the treatment of cancer cells. This drug is a structural analog of salicylic acid, which also exhibits anti-inflammatory, antipyretic and analgesic properties. Methyl 5-iodosalicylate is chiral and bioisosteric with salicylic acid. It has been shown to inhibit the proliferation of human colon cancer cells in vitro. The anticancer activity of methyl 5-iodosalicylate may be due to its ability to induce apoptosis in cancer cells by inhibiting DNA synthesis and RNA transcription. Methyl 5-iodosalicylate also inhibits DNA synthesis through competitive inhibition of deoxyribonucleotide triphosphates (dNTPs).

Formula: C₈H₇IO₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 278.04 g/mol

Ref: 3D-FM70651

Methyl 5-iodosalicylate

CAS: 4068-75-1

Formula: C₈H₇IO₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 278.045

Ref: 10-F325132

Methyl 2-hydroxy-5-iodobenzoate

CAS: 4068-75-1

Formula: C₈H₇IO₃

Purity: 98.0 min. % GC/98.0 min. % HPLC

Color and Shape: White to off white solid

Molecular weight: 278.04

Ref: 08-M205