CAS 40722-73-4
:2H-1,3,2-Oxazaphosphorine, 2-chloro-3-(2-chloroethyl)tetrahydro-, 2-oxide
Description:
2H-1,3,2-Oxazaphosphorine, 2-chloro-3-(2-chloroethyl)tetrahydro-, 2-oxide, commonly known as a derivative of oxazaphosphorine, is a chemical compound characterized by its unique structure that includes a phosphorus atom integrated into a heterocyclic ring containing nitrogen and oxygen. This compound typically exhibits properties associated with both phosphorines and chlorinated organic compounds, including potential reactivity due to the presence of chlorine substituents. It is often utilized in medicinal chemistry and as an intermediate in the synthesis of various pharmaceuticals. The compound may demonstrate moderate to high stability under standard conditions but can be sensitive to hydrolysis and other nucleophilic attacks due to the electrophilic nature of the phosphorus center. Additionally, its biological activity may be influenced by the presence of the chloroethyl groups, which can participate in alkylation reactions. Safety data should be consulted, as compounds of this class may pose health risks, including toxicity and potential carcinogenicity. Proper handling and disposal procedures are essential when working with such substances.
Formula:C5H10Cl2NO2P
InChI:InChI=1S/C5H10Cl2NO2P/c6-2-4-8-3-1-5-10-11(8,7)9/h1-5H2
InChI key:InChIKey=SBMJSKYKTAAHAB-UHFFFAOYSA-N
SMILES:C(CCl)N1P(Cl)(=O)OCCC1
Synonyms:- 2H-1,3,2-Oxazaphosphorine, 2-chloro-3-(2-chloroethyl)tetrahydro-, 2-oxide
- 2-Chloro-3-(2-chloroethyl)-1,3,2λ5-oxazaphosphinan-2-one
- 2-Chloro-3-(2-chloroethyl)perhydro-1,3,2λ5-oxazaphosphorin-2-one
- (Rs)-2-chloro-3-(2-chloroethyl)-1,3,2-oxazaphosphinane 2-oxide
- Ifosfamide Impurity 15
- Ifosfamide impurity F CRS
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