CAS 40733-27-5: Thymidine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-
CAS 40733-27-5: Thymidine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-
Description:Thymidine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]- is a modified nucleoside derivative of thymidine, which is one of the four nucleosides that make up DNA. This compound features a silyl ether group at the 3' position of the ribose sugar, specifically a tert-butyldimethylsilyl (TBDMS) group, which enhances its stability and solubility in organic solvents. The presence of the silyl group can also facilitate various chemical reactions, making it useful in synthetic organic chemistry, particularly in the synthesis of oligonucleotides. The compound is typically a white to off-white solid and is soluble in common organic solvents. Its molecular structure allows for specific interactions in biochemical applications, and it is often utilized in research settings for DNA synthesis and modification. As with many chemical substances, proper handling and storage conditions are essential to maintain its integrity and prevent degradation.
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