CAS 40733-27-5

Thymidine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-

Description:

Thymidine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]- is a modified nucleoside derivative of thymidine, which is one of the four nucleosides that make up DNA. This compound features a silyl ether group at the 3' position of the ribose sugar, specifically a tert-butyldimethylsilyl (TBDMS) group, which enhances its stability and solubility in organic solvents. The presence of the silyl group can also facilitate various chemical reactions, making it useful in synthetic organic chemistry, particularly in the synthesis of oligonucleotides. The compound is typically a white to off-white solid and is soluble in common organic solvents. Its molecular structure allows for specific interactions in biochemical applications, and it is often utilized in research settings for DNA synthesis and modification. As with many chemical substances, proper handling and storage conditions are essential to maintain its integrity and prevent degradation.

Formula: C₁₆H₂₈N₂O₅Si

3'-O-[tert-Butyl(dimethyl)silyl]thymidine

CAS: 40733-27-5

Formula: C₁₆H₂₈N₂O₅Si

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 356.49

Ref: 3B-D5997

Thymidine, 3'-O-[(1,1-dimethylethyl)dimethylsilyl]-

CAS: 40733-27-5

Formula: C₁₆H₂₈N₂O₅Si

Purity: 97%

Color and Shape: Solid

Molecular weight: 356.4894

Ref: IN-DA00C0M4

1-((2R,4S,5R)-4-((Tert-Butyldimethylsilyl)Oxy)-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)-5-Methylpyrimidine-2,4(1H,3H)-Dione

CAS: 40733-27-5

1-((2R,4S,5R)-4-((Tert-Butyldimethylsilyl)Oxy)-5-(Hydroxymethyl)Tetrahydrofuran-2-Yl)-5-Methylpyrimidine-2,4(1H,3H)-Dione

Purity: 97%

Molecular weight: 356.49g/mol

Ref: 54-OR1027692

3'-O-t-Bulyldimethylsilyl thymidine

CAS: 40733-27-5

Nucleosides - 2’-deoxynucleoside

Formula: C₁₆H₂₈N₂O₅Si

Color and Shape: Solid

Molecular weight: 356.49

Ref: TM-TNU0727

1-((2R,4S,5R)-4-((tert-Butyldimethylsilyl)oxy)-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

CAS: 40733-27-5

Formula: C₁₆H₂₈N₂O₅Si

Purity: 97%

Color and Shape: Solid

Molecular weight: 356.494

Ref: 10-F541400

3’-O-t-Bulyldimethylsilyl thymidine

CAS: 40733-27-5

3’-O-t-Bulyldimethylsilyl thymidine is a nucleoside analog that is chemically stable and has been shown to be a potential biomarker for the diagnosis of fetal bovine spongiform encephalopathy (BSE). 3’-O-t-Bulyldimethylsilyl thymidine binds to basic proteins in the cell nucleus, which can be detected by immunoassay. It also has been shown to inhibit protein synthesis in tubule cells of the kidney and skin cancer cells. The drug is metabolized by dephosphorylation to t-butyldeoxyuridine, which is then converted into thymidine.

Formula: C₁₆H₂₈N₂O₅Si

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 356.49 g/mol

Ref: 3D-FB144782