CAS 40738-83-8

5-iodo-1,3-dimethyluracil

Description:

5-Iodo-1,3-dimethyluracil is a halogenated derivative of uracil, a pyrimidine nucleobase. This compound features an iodine atom at the 5-position and two methyl groups at the 1 and 3 positions of the uracil ring. Its molecular structure contributes to its unique chemical properties, including its potential as a nucleoside analog, which can interfere with nucleic acid synthesis. The presence of the iodine atom enhances its lipophilicity, potentially affecting its biological activity and interactions with enzymes or receptors. 5-Iodo-1,3-dimethyluracil may exhibit various pharmacological effects, making it of interest in medicinal chemistry and drug development. Additionally, its stability and solubility in organic solvents can influence its application in research and industry. As with many halogenated compounds, it is essential to handle it with care due to potential toxicity and environmental impact. Overall, this compound exemplifies the diverse modifications that can be made to nucleobases to explore their biological functions and therapeutic potentials.

Formula: C₆H₇IN₂O₂

InChI: InChI=1/C6H7IN2O2/c1-8-3-4(7)5(10)9(2)6(8)11/h3H,1-2H3

SMILES: Cn1cc(c(=O)n(C)c1=O)I

Synonyms:

• 5-iodo-1,3-dimethylpyrimidine-2,4(1H,3H)-dione

5-Iodo-1,3-dimethyluracil, 99%

CAS: 40738-83-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₆H₇IN₂O₂

Purity: 99%

Color and Shape: White, Crystals or powder or crystalline powder

Molecular weight: 266.04

Ref: 02-B25173

2,4(1H,3H)-Pyrimidinedione, 5-iodo-1,3-dimethyl-

CAS: 40738-83-8

Formula: C₆H₇IN₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 266.0364

Ref: IN-DA00I7ZO

5-Iodo-1,3-dimethylpyrimidine-2,4-dione

CAS: 40738-83-8

5-Iodo-1,3-dimethylpyrimidine-2,4-dione

Purity: 98%

Molecular weight: 266.04g/mol

Ref: 54-OR90510

5-Iodo-1,3-dimethylpyrimidine-2,4(1H,3H)-dione

CAS: 40738-83-8

Formula: C₆H₇IN₂O₂

Purity: 98%

Molecular weight: 266.038

Ref: 10-F212436

5-Iodo-1,3-dimethyluracil

CAS: 40738-83-8

5-Iodo-1,3-dimethyluracil (5IDMU) is a nucleoside that is used in cancer diagnosis. 5IDMU can be synthesized by the Suzuki coupling reaction with an amine and a halide. The synthesis of 5IDMU can also be accomplished by the cross-coupling of an amine and a tautomeric methylene compound. The methylene group in the heterocycle is electron donating, which makes it more reactive than other groups. This nucleoside has been shown to have anti-inflammatory properties, which may be due to its ability to inhibit prostaglandin synthesis. 5IDMU has also been shown to have anticancer effects in vitro and in vivo.

Formula: C₆H₇IN₂O₂

Purity: Min. 95%

Molecular weight: 266.04 g/mol

Ref: 3D-QBA73883