CAS 407581-83-3

1,4-dichloro 6-Carboxytetramethylrhodamine

Description:

1,4-Dichloro 6-Carboxytetramethylrhodamine, with the CAS number 407581-83-3, is a synthetic organic compound belonging to the rhodamine family, which are known for their fluorescent properties. This compound features a rhodamine core structure modified with two chlorine atoms at the 1 and 4 positions and a carboxylic acid group at the 6 position, enhancing its solubility in aqueous environments. It exhibits strong fluorescence, making it useful in various applications such as biological imaging, fluorescence microscopy, and as a tracer in biochemical assays. The presence of the carboxylic acid group allows for potential conjugation with biomolecules, facilitating its use in targeted delivery systems. Additionally, the dichloro substitutions can influence the compound's photostability and spectral properties. Overall, 1,4-Dichloro 6-Carboxytetramethylrhodamine is valued for its versatility in research and diagnostic applications due to its bright fluorescence and functional modifications.

2-(3,6-Bis(dimethylamino)xanthylium-9-yl)-4-carboxy-3,6-dichlorobenzoate

CAS: 407581-83-3

Formula: C₂₅H₂₀Cl₂N₂O₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 499.3427

Ref: IN-DA00CJ0U

1,4-dichloro 6-Carboxytetramethylrhodamine

CAS: 407581-83-3

1,4-Dichloro 6-carboxytetramethylrhodamine (1,4-DCTMR) is a fluorescent dye that can be used to measure the activity of HIV reverse transcriptase. 1,4-DCTMR binds tightly to some residues in the enzyme's active site and fluoresces when it is irradiated with light at the wavelength of 490 nm. It has been shown that HIV mutants are resistant to zidovudine treatment. When a population of HIV mutants is exposed to zidovudine, there will be an increase in the number of mutant viruses that are resistant to zidovudine. The use of 1,4-DCTMR can be used as a marker for these resistant viruses and can help determine which mutations have occurred. 1,4-DCTMR is also used in research to study transcription polymerase chain reaction sequences and mutant populations.

Formula: C₂₅H₂₀Cl₂N₂O₅

Purity: Min. 95%

Molecular weight: 499.34 g/mol

Ref: 3D-FD76920

1,4-Dichloro 6-carboxytetramethylrhodamine

CAS: 407581-83-3

1,4-Dichloro 6-carboxytetramethylrhodamine is a rhodamine-class fluorescent dye with excitation/emission wavelengths of 541/568 nm.

Formula: C₂₅H₂₀Cl₂N₂O₅

Purity: 99.99%

Color and Shape: Solid

Molecular weight: 499.34

Ref: TM-T18879