CAS 407582-49-4

2-[4-(2-Carboxypropoxy)-3-cyanophenyl]-4-methyl-5-thiazolecarboxylic acid

Description:

2-[4-(2-Carboxypropoxy)-3-cyanophenyl]-4-methyl-5-thiazolecarboxylic acid, with the CAS number 407582-49-4, is a chemical compound characterized by its complex structure, which includes a thiazole ring, a carboxylic acid group, and a cyanophenyl moiety. This compound typically exhibits properties such as solubility in polar solvents due to the presence of carboxylic acid and ether functionalities. It may also demonstrate biological activity, potentially serving as a pharmaceutical intermediate or a lead compound in drug development, particularly in areas related to anti-inflammatory or anticancer research. The thiazole ring contributes to its aromatic character, which can influence its reactivity and interaction with biological targets. Additionally, the presence of multiple functional groups suggests that it may participate in various chemical reactions, including esterification and amidation. Overall, this compound's unique structural features make it of interest in both synthetic chemistry and medicinal chemistry applications.

Formula: C₁₆H₁₄N₂O₅S

InChI: InChI=1S/C16H14N2O5S/c1-8(15(19)20)7-23-12-4-3-10(5-11(12)6-17)14-18-9(2)13(24-14)16(21)22/h3-5,8H,7H2,1-2H3,(H,19,20)(H,21,22)

InChI key: InChIKey=LCBACLAPKJRMIF-UHFFFAOYSA-N

SMILES: C(O)(=O)C=1SC(=NC1C)C2=CC(C#N)=C(OCC(C(O)=O)C)C=C2

Synonyms:

• 2-[4-(2-Carboxypropoxy)-3-cyanophenyl]-4-methyl-5-thiazolecarboxylic acid
• 5-Thiazolecarboxylic acid, 2-[4-(2-carboxypropoxy)-3-cyanophenyl]-4-methyl-

Febuxostat Metabolite 67M-4

CAS: 407582-49-4

Formula: C₁₆H₁₄N₂O₅S

Molecular weight: 346.36

Ref: 4Z-F-3994

Febuxostat 67M-4

Controlled Product

CAS: 407582-49-4

Applications Febuxostat 67M-4 is a derivative compound of Febuxostat 67M-1 (F229005) which is an inhibitor of xanthine oxidase. It reduces uric acid production in the body and also used to reduce the risk of gout or kidney stone formation.
References Du, J., et al.: Handbook of Metabolic Pathways of Xenobiotics, 4, 1395 (2014)

Formula: C₁₆H₁₄N₂O₅S

Color and Shape: Neat

Molecular weight: 346.36

Ref: TR-F229015

Febuxostat 67M-4

CAS: 407582-49-4

Febuxostat is a potent, selective inhibitor of the enzyme xanthine oxidoreductase (XOR). This enzyme is involved in the production of uric acid and its inhibition leads to a decrease in serum uric acid levels. Febuxostat is used for the treatment of chronic gouty arthritis, hyperuricemia associated with primary or secondary causes, and asymptomatic hyperuricemia.
Febuxostat was shown to bind to a number of different receptors and ion channels, including the purinergic receptor P2Y1, ATP-sensitive potassium channel KATP, transient receptor potential ankyrin 1 channel TRPA1 and TRPV1. It also interacts with peptides such as vasopressin V1a receptor antagonist [8] and alpha-2 adrenergic receptor antagonist [9].

Formula: C₁₆H₁₄N₂O₅S

Purity: Min. 95%

Molecular weight: 346.4 g/mol

Ref: 3D-HRA58249

Febuxostat Impurity 40

CAS: 407582-49-4

Formula: C₁₆H₁₄N₂O₅S

Molecular weight: 346.36

Ref: ST-EA-CP-F7058

Febuxostat 67M-4

CAS: 407582-49-4

Febuxostat 67M-4, a derivative of 67M-1, inhibits xanthine oxidase to lower uric acid and gout/kidney stone risk.

Formula: C₁₆H₁₄N₂O₅S

Color and Shape: Solid

Molecular weight: 346.36

Ref: TM-T69281