CAS 40796-97-2

Bemesetron

Description:

Bemesetron is a chemical compound classified as a selective serotonin 5-HT3 receptor antagonist, primarily used in the medical field for its antiemetic properties, particularly in the prevention of nausea and vomiting associated with chemotherapy and surgery. It is characterized by its ability to block the action of serotonin at the 5-HT3 receptors in the central nervous system and gastrointestinal tract, thereby reducing the sensation of nausea. The compound has a specific molecular structure that contributes to its pharmacological activity, and it is typically administered in a clinical setting. Bemesetron is known for its relatively high potency and efficacy in managing emesis, making it a valuable option in supportive cancer care. Additionally, it has undergone various studies to assess its safety profile and potential side effects, which are generally mild and manageable. As with any medication, its use should be guided by a healthcare professional, taking into account individual patient needs and conditions.

Formula: C₁₅H₁₇Cl₂NO₂

InChI: InChI=1/C15H17Cl2NO2/c1-18-12-2-3-13(18)8-14(7-12)20-15(19)9-4-10(16)6-11(17)5-9/h4-6,12-14H,2-3,7-8H2,1H3/t12-,13+,14+

InChI key: InChIKey=MNJNPLVXBISNSX-WDNDVIMCNA-N

SMILES: O(C(=O)C1=CC(Cl)=CC(Cl)=C1)[C@H]2C[C@@]3(N(C)[C@](C2)(CC3)[H])[H]

Synonyms:

• (1R,5S)-3-[(3,5-dichlorobenzoyl)oxy]-8-methyl-8-azoniabicyclo[3.2.1]octane
• (1R,5S)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl 3,5-dichlorobenzoate
• (3-Endo)-8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl 3,5-Dichlorobenzoate
• 8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl 3,5-Dichlorobenzoate
• Bemesetron
• Benzoic acid, 3,5-dichloro-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester
• Benzoic acid, 3,5-dichloro-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, endo-
• Mdl 72222

3-Tropanyl-3,5-dichlorobenzoate

CAS: 40796-97-2

Formula: C₁₅H₁₇Cl₂NO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 314.2070

Ref: IN-DA00BZM8

3-Tropanyl-3,5-Dichlorobenzoate

CAS: 40796-97-2

3-Tropanyl-3,5-Dichlorobenzoate

Purity: 99%

Molecular weight: 314.21g/mol

Ref: 54-OR1024239

Bemesetron

CAS: 40796-97-2

Bemesetron

Purity: ≥95%

Molecular weight: 314.21g/mol

Ref: 54-BUP11541

MDL 72222

CAS: 40796-97-2

MDL 72222 is a selective serotonin receptor antagonist, which is primarily used for research purposes. It is a synthetic compound specifically designed to block the 5-HT3 subtype of serotonin receptors. The mode of action of MDL 72222 involves competitive inhibition at the 5-HT3 receptor site, which is known for its role in neurotransmitter regulation within the central and peripheral nervous systems.

Formula: C₁₅H₁₇Cl₂NO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 314.21 g/mol

Ref: 3D-QBA79697

MDL-72222

Controlled Product

CAS: 40796-97-2

Formula: C₁₅H₁₇Cl₂NO₂

Color and Shape: Neat

Molecular weight: 314.207

Ref: TR-M199805

Bemesetron

CAS: 40796-97-2

Bemesetron (MDL 72222) is a selective antagonist of 5-HT3 (IC50 = 0.33 nM) with neuroprotective effects.

Formula: C₁₅H₁₇Cl₂NO₂

Purity: 99.77%

Color and Shape: Solid

Molecular weight: 314.21

Ref: TM-T14526