CAS 4083-64-1

p-Toluenesulfonyl isocyanate

Description:

p-Toluenesulfonyl isocyanate (CAS 4083-64-1) is an organic compound characterized by its isocyanate functional group attached to a p-toluenesulfonyl moiety. It appears as a colorless to pale yellow liquid and is known for its reactivity, particularly in the formation of ureas and carbamates through nucleophilic addition reactions. This compound is soluble in organic solvents such as acetone and dichloromethane but is generally insoluble in water. p-Toluenesulfonyl isocyanate is utilized in organic synthesis, particularly in the preparation of various pharmaceuticals and agrochemicals, due to its ability to introduce isocyanate functionalities into molecules. It is important to handle this compound with care, as it can be toxic and irritating to the skin, eyes, and respiratory system. Proper safety precautions, including the use of personal protective equipment and working in a well-ventilated area, are essential when working with this chemical.

Formula: C₈H₇NO₃S

InChI: InChI=1S/C8H7NO3S/c1-7-2-4-8(5-3-7)13(11,12)9-6-10/h2-5H,1H3

InChI key: InChIKey=VLJQDHDVZJXNQL-UHFFFAOYSA-N

SMILES: S(N=C=O)(=O)(=O)C1=CC=C(C)C=C1

Synonyms:

• 4-Methylbenzenesulfonyl Isocyanate
• 4-Methylphenylsulfonyl isocyanate
• 4-Toluenesulfonyl isocyanate
• 4-Toluolsulfonyl isocyanate
• Additive TI
• Benzenesulfonyl isocyanate, 4-methyl-
• HK-additive TI
• Isocyanic acid, anhydride with p-toluenesulfonic acid
• Ptsi
• Toluenesulfonyl isocyanate
• Tosyl isocyanate
• p-Methylbenzenesulfonyl isocyanate
• p-Methylphenylsulfonyl isocyanate
• p-Methylphenylsulfonyl lsocyanate
• p-Toluenesulfonic acid, anhydride with isocyanic acid
• p-Tosyl isocyanate

p-Toluenesulfonyl Isocyanate

CAS: 4083-64-1

Formula: C₈H₇NO₃S

Purity: >95.0%(T)

Color and Shape: Colorless to Almost colorless clear liquid

Molecular weight: 197.21

Ref: 3B-T0998

p-Toluenesulfonyl isocyanate, 95%

CAS: 4083-64-1

It is a reagent used to prepare acetylated syn-1,2-diols,oxazolidin-2-ones, 2,3-diamino acids, and N-tosylcarbonamides. -Toluenesulfonyl isocyanate has been used as derivatization reagent in determination of 3--hydroxy tibolone in human plasma by LC-MS/MS. It is also employed in the derivatization r

Formula: C₈H₇NO₃S

Purity: 95%

Color and Shape: Clear colorless to pale yellow, Liquid

Molecular weight: 197.21

Ref: 02-A17492

Tosyl Isocyanate

CAS: 4083-64-1

Formula: C₈H₇NO₃S

Purity: 95%

Color and Shape: Liquid

Molecular weight: 197.2111

Ref: IN-DA003UUB

4-Methylbenzene-1-sulphonyl isocyanate

CAS: 4083-64-1

4-Methylbenzene-1-sulphonyl isocyanate

Formula: C₈H₇NO₃S

Purity: 98%

Color and Shape: clear. colourless liquid

Molecular weight: 197.21g/mol

Ref: 54-OR28867

p-Toluenesulfonyl isocyanate

CAS: 4083-64-1

Formula: C₈H₇NO₃S

Purity: 95%

Color and Shape: Liquid

Molecular weight: 197.21

Ref: 10-F494399

p-Toluenesulfonyl Isocyanate

Controlled Product

CAS: 4083-64-1

Applications p-Toluenesulfonyl Isocyanate has been used to react with a prepolymer with the OH-functionality.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Muenker, A.H., Hudson, B.E.: J. Macromol. Sci. Chem., 3, 1465 (1969)

Formula: C₈H₇NO₃S

Color and Shape: Neat

Molecular weight: 197.21

Ref: TR-T535960

p-Toluenesulfonyl-d7 Isocyanate

Controlled Product

CAS: 4083-64-1

Formula: C₈D₇NO₃S

Color and Shape: Neat

Molecular weight: 204.254

Ref: TR-T535962

p-Toluenesulfonyl isocyanate

CAS: 4083-64-1

p-Toluenesulfonyl isocyanate (PTSA) is a reactive chemical that reacts with hydroxyl groups to form covalent bonds. It can be used as a cross-linking agent for polymers, sealant, or chemical ligation in the laboratory. PTSA also has potent inhibition of nucleophilic attack on aromatic rings and is therefore used as a reagent in organic synthesis. This compound can react with amines to produce N-sulfonylureas and N-sulfonylimines, which are used in pharmaceuticals and other synthetic reactions. PTSA is also used in electrochemical impedance spectroscopy to measure the impedance of metal electrodes.

Formula: C₈H₇NO₃S

Purity: Min. 96 Area-%

Color and Shape: Clear Liquid

Molecular weight: 197.21 g/mol

Ref: 3D-FT04160