CAS 4084-27-9
:3-Deoxyglucosone
Description:
3-Deoxyglucosone (3-DG) is a reactive dicarbonyl compound derived from glucose metabolism. It is characterized by its structure, which features a ketone and an aldehyde functional group, making it a potent precursor in the formation of advanced glycation end products (AGEs). These AGEs are implicated in various pathological conditions, including diabetes and cardiovascular diseases. 3-DG is known for its ability to react with amino acids, proteins, and nucleic acids, leading to modifications that can affect cellular function and contribute to oxidative stress. The compound is typically present in trace amounts in biological systems and can be formed through non-enzymatic glycation processes. Its reactivity and potential biological effects make it a subject of interest in research related to metabolic disorders and aging. Additionally, 3-Deoxyglucosone can be analyzed using various techniques, including chromatography and mass spectrometry, to study its role in health and disease.
Formula:C6H10O5
InChI:InChI=1S/C6H10O5/c7-2-4(9)1-5(10)6(11)3-8/h2,5-6,8,10-11H,1,3H2/t5-,6+/m0/s1
InChI key:InChIKey=ZGCHLOWZNKRZSN-NTSWFWBYSA-N
SMILES:[C@H](CC(C=O)=O)([C@@H](CO)O)O
Synonyms:- 2-keto-3-Deoxyglucose
- 3-Deoxy-<span class="text-smallcaps">D</span>-erythro-hexos-2-ulose
- 3-Deoxy-<span class="text-smallcaps">D</span>-erythro-hexosulose
- 3-Deoxy-<span class="text-smallcaps">D</span>-glucosone
- 3-Deoxyglucosone
- <span class="text-smallcaps">D</span>-erythro-Hexos-2-ulose, 3-deoxy-
- <span class="text-smallcaps">D</span>-erythro-Hexosulose, 3-deoxy-
- D-erythro-hexos-2-ulose, 3-deoxy-
- 3-Deoxy-D-erythro-hexosulose
- D-erythro-Hexosulose, 3-deoxy-
- 3-Deoxy-D-erythro-hexos-2-ulose
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Found 9 products.
3-Deoxy-D-glucosone, 95%
CAS:<p>Frequently used as a reference for the analysis and detection of glucose degradation products and glycating agents. Also used for cross-linking studies as it readily reacts with protein amino groups. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfol</p>Formula:C6H10O5Purity:95%Color and Shape:Yellow, Powder or crystals or crystalline powderMolecular weight:162.143-Deoxy-D-glucosone
CAS:<p>3-Deoxy-D-glucosone</p>Formula:C6H10O5Purity:>95%Color and Shape: yellow amorphous solidMolecular weight:162.14g/mol3-Deoxy-D-erythro-hexos-2-ulose
CAS:<p>3-Deoxy-D-erythro-hexos-2-ulose</p>Purity:≥95%Color and Shape:Pale Yellow SolidMolecular weight:162.14g/mol3-Deoxyglucosone
CAS:<p>3-Deoxyglucosone(3-Deoxy-D-glucosone) is synthesized by the intermediate pathway of the melad and polyol reactions.3-Deoxyglucosone reacts rapidly with protein</p>Formula:C6H10O5Purity:95%Color and Shape:SolidMolecular weight:162.143-Deoxyglucosone
CAS:Formula:C6H10O5Purity:One spotColor and Shape:Pale yellow to yellow powder or solidMolecular weight:162.143-Deoxyglucosone
CAS:<p>Stability Hygroscopic, Light Sensitive, Temperature Sensitive<br>Applications An intermediate in the Maillard reaction of proteins with glucose, which is metabolised to 3-Deoxyfructose. An intermediate in the formation of pyrraline, which might contribute to a pathological effect, such as carcinogenesis.<br>References Kato, H. et al.: Agric. Biol. Chem., 51, 683 (1987), Hayase, F. et al.: J. Biol. Chem., 264, 3758 (1989), Kato, H. et al.: Biochimica et Biophysica Acta, 1035, 71 (1990)<br></p>Formula:C6H10O5Color and Shape:White To YellowMolecular weight:162.143-Deoxy-D-glucosone
CAS:<p>3-Deoxy-D-glucosone is a compound that belongs to the group of monosaccharides and has a basic structure. It can be found in many types of biological samples, including blood. The x-ray diffraction data for 3-deoxy-D-glucosone shows an asymmetric unit of two molecules with a coordination geometry of 2.3. This compound is known to have high protein oxidation rates, which are caused by dna binding activity. 3-Deoxyglucosone has been shown to be involved in the pathogenic mechanism of many types of cancers.</p>Formula:C6H10O5Purity:Min. 95%Color and Shape:PowderMolecular weight:162.14 g/mol
