CAS 408504-26-7

Sergliflozin etabonate

Description:

Sergliflozin etabonate is a pharmaceutical compound primarily used in the treatment of type 2 diabetes mellitus. It functions as a selective inhibitor of the sodium-glucose co-transporter 2 (SGLT2), which plays a crucial role in glucose reabsorption in the kidneys. By inhibiting this transporter, sergliflozin etabonate promotes the excretion of glucose in urine, thereby lowering blood glucose levels. The compound is characterized by its chemical structure, which includes a specific arrangement of functional groups that contribute to its biological activity and pharmacokinetic properties. It is typically administered orally and has been studied for its efficacy and safety profile in clinical settings. Additionally, sergliflozin etabonate may have beneficial effects on weight management and cardiovascular health, making it a valuable option in diabetes care. As with any medication, potential side effects and contraindications should be considered, and it is essential for patients to consult healthcare professionals for personalized advice and treatment plans.

Formula: C₂₃H₂₈O₉

InChI: InChI=1S/C23H28O9/c1-3-29-23(27)30-13-18-19(24)20(25)21(26)22(32-18)31-17-7-5-4-6-15(17)12-14-8-10-16(28-2)11-9-14/h4-11,18-22,24-26H,3,12-13H2,1-2H3/t18-,19-,20+,21-,22-/m1/s1

InChI key: InChIKey=QLXKHBNJTPICNF-QMCAAQAGSA-N

SMILES: O(C1=C(CC2=CC=C(OC)C=C2)C=CC=C1)[C@@H]3O[C@H](COC(OCC)=O)[C@@H](O)[C@H](O)[C@H]3O

Synonyms:

• 2-[(4-Methoxyphenyl)methyl]phenyl-beta-D-glucopyranoside-6-(ethyl carbonate)
• Gw 869682X
• Loteprednola Etabonate
• β-<span class="text-smallcaps">D</span>-Glucopyranoside, 2-[(4-methoxyphenyl)methyl]phenyl, 6-(ethyl carbonate)
• β-D-Glucopyranoside, 2-[(4-methoxyphenyl)methyl]phenyl, 6-(ethyl carbonate)
• Sergliflozin etabonate

Sergliflozin etabonate

CAS: 408504-26-7

Sergliflozin etabonate

Purity: ≥95%

Molecular weight: 448.46g/mol

Ref: 54-BUP03167

2-(4-Methoxybenzyl)phenyl6-O-(ethoxycarbonyl)-β-D-glucopyranoside

Controlled Product

CAS: 408504-26-7

Formula: C₂₃H₂₈O₉

Color and Shape: Neat

Molecular weight: 448.463

Ref: TR-M208745

2-(4-Methoxybenzyl)phenyl6-O-(ethoxycarbonyl)-β-D-glucopyranoside

CAS: 408504-26-7

Canagliflozin is a type of antidiabetic agent that is used to treat patients with type 2 diabetes. This drug works by decreasing the reabsorption of glucose in the kidneys, which increases the excretion of glucose, and thus reduces blood sugar levels. Canagliflozin also lowers blood pressure and has been shown to reduce cholesterol levels. It is an inhibitor of SGLT-1, a transporter protein in the kidney that is responsible for renal glucose reabsorption. The use of canagliflozin has been studied in animal models, where it was found to significantly increase glomerular filtration rate (GFR) and decrease blood pressure. It is recommended that canagliflozin be taken together with other anti-diabetic medications, such as insulin or metformin, due to its potential side effects on GFR and blood pressure.

Formula: C₂₃H₂₈O₉

Purity: Min. 95%

Molecular weight: 448.46 g/mol

Ref: 3D-FM152924

Sergliflozin etabonate

CAS: 408504-26-7

Sergliflozin etabonate (KGT-1251) is an inhibitor of SGLT2 and can be used in studies about type 2 diabetes and obesity.

Formula: C₂₃H₂₈O₉

Purity: 97.88%

Color and Shape: Solid

Molecular weight: 448.46

Ref: TM-T28757