CAS 4089-36-5

(11β,16α)-17,21-Epoxy-9-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione

Description:

The chemical substance known as "(11β,16α)-17,21-Epoxy-9-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione," with the CAS number 4089-36-5, is a synthetic corticosteroid. It exhibits anti-inflammatory and immunosuppressive properties, making it useful in various therapeutic applications, particularly in treating conditions such as asthma, allergies, and autoimmune disorders. The structure of this compound features a fluorine atom, which enhances its potency and metabolic stability compared to other corticosteroids. The presence of an epoxy group contributes to its unique reactivity and biological activity. Additionally, the hydroxyl and methyl groups play crucial roles in modulating its pharmacological effects. As a corticosteroid, it mimics the action of cortisol, a natural hormone produced by the adrenal glands, and influences numerous physiological processes, including metabolism, immune response, and stress response. Due to its potent effects, it is essential to use this compound under medical supervision to manage potential side effects associated with corticosteroid therapy.

Formula: C₂₂H₂₇FO₄

InChI: InChI=1/C22H27FO4/c1-12-8-16-15-5-4-13-9-14(24)6-7-19(13,2)21(15,23)17(25)10-20(16,3)22(12)18(26)11-27-22/h6-7,9,12,15-17,25H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21?,22?/m1/s1

InChI key: InChIKey=PLIOZIVVVLFDAA-CXSFZGCWSA-N

SMILES: C[C@@]12[C@]3([C@H](C)C[C@]1([C@]4([C@](F)([C@@H](O)C2)[C@]5(C)C(CC4)=CC(=O)C=C5)[H])[H])C(=O)CO3

Synonyms:

• (11β,16α)-17,21-Epoxy-9-fluoro-11-hydroxy-16-methylpregna-1,4-diene-3,20-dione
• Pregna-1,4-diene-3,20-dione, 17,21-epoxy-9-fluoro-11β-hydroxy-16α-methyl-
• Pregna-1,4-diene-3,20-dione, 17,21-epoxy-9-fluoro-11-hydroxy-16-methyl-, (11β,16α)-
• Dexamethasone oxetanone
• (8S,10S,11S,13S,14S,16R)-9-fluoro-11-hydroxy-10,13,16-trimethylspiro[6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthrene-17,2'-oxetane]-3,3'-dione

Dexamethasone Oxetanone

CAS: 4089-36-5

Formula: C₂₂H₂₇FO₄

Color and Shape: Pale Yellow Solid

Molecular weight: 374.45

Ref: 4Z-D-3635

Dexamethasone Oxetanone

CAS: 4089-36-5

Color and Shape: Neat

Ref: 86-MM0213.20

Dexamethasone Oxetanone

CAS: 4089-36-5

Formula: C₂₂H₂₇FO₄

Molecular weight: 374.45

Ref: ST-EA-CP-D17015

Dexamethasone Oxetanone

Controlled Product

CAS: 4089-36-5

Applications Dexamethasone Oxetanone is a potent antiglucocorticoid.
References Lamontagne, N., et al.: Endocrinology, 114, 2252 (1984);

Formula: C₂₂H₂₇FO₄

Color and Shape: Neat

Molecular weight: 374.45

Ref: TR-D298875

Dexamethasone oxetanone

CAS: 4089-36-5

Please enquire for more information about Dexamethasone oxetanone including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₂₂H₂₇FO₄

Purity: Min. 95%

Molecular weight: 374.4 g/mol

Ref: 3D-FD182373

Dexamethasone oxetanone

CAS: 4089-36-5

Dex-Ox, a selective glucocorticoid derivative of Dex, exhibits antiglucocorticoid and antiprogestin activities, targeting PR A/B isoforms.

Formula: C₂₂H₂₇FO₄

Color and Shape: Solid

Molecular weight: 374.45

Ref: TM-T61525