CAS 409345-29-5

(3,4-Dihydro-2H-pyrano[2,3-b]quinolin-7-yl)(cis-4-methoxycyclohexyl)methanone

Description:

(3,4-Dihydro-2H-pyrano[2,3-b]quinolin-7-yl)(cis-4-methoxycyclohexyl)methanone is a complex organic compound characterized by its unique structural features, which include a pyranoquinoline core and a methanone functional group. This compound exhibits a bicyclic structure that contributes to its potential biological activity. The presence of the methoxy group on the cyclohexyl ring enhances its lipophilicity, which may influence its interaction with biological membranes and receptors. The stereochemistry indicated by the "cis" configuration suggests specific spatial arrangements that can affect the compound's reactivity and binding properties. Such compounds are often of interest in medicinal chemistry due to their potential pharmacological applications, including anti-inflammatory or anticancer activities. Additionally, the compound's molecular weight, solubility, and stability under various conditions would be critical for its practical applications in research or therapeutic contexts. Overall, this compound represents a fascinating area of study within organic and medicinal chemistry, warranting further investigation into its properties and potential uses.

Formula: C₂₀H₂₃NO₃

InChI: InChI=1/C20H23NO3/c1-23-17-7-4-13(5-8-17)19(22)14-6-9-18-16(11-14)12-15-3-2-10-24-20(15)21-18/h6,9,11-13,17H,2-5,7-8,10H2,1H3/t13-,17+

InChI key: InChIKey=QOTAQTRFJWLFCR-XFHMXUHZNA-N

SMILES: C(=O)(C1=CC2=C(N=C3C(=C2)CCCO3)C=C1)[C@H]4CC[C@@H](OC)CC4

Synonyms:

• JNJ 16259685
• (3,4-Dihydro-2H-pyrano[2,3-b]quinolin-7-yl)(cis-4-methoxycyclohexyl)methanone
• Methanone, (3,4-dihydro-2H-pyrano[2,3-b]quinolin-7-yl)(cis-4-methoxycyclohexyl)-

(3,4-Dihydro-2H-pyrano[2,3-b]quinolin-7-yl)-(cis-4-methoxycyclohexyl)-methanone

CAS: 409345-29-5

Formula: C₂₀H₂₃NO₃

Purity: 96%

Color and Shape: Solid

Molecular weight: 325.4015

Ref: IN-DA0037HA

JNJ16259685

CAS: 409345-29-5

JNJ16259685

Purity: ≥98%

Molecular weight: 325.4g/mol

Ref: 54-BUP04888

JNJ16259685

CAS: 409345-29-5

JNJ16259685 (TN.T 16259685) is a selective mGluR1 antagonist, and inhibits the synaptic activation of mGluR1 in a concentration-dependent manner with IC50 of 19

Formula: C₂₀H₂₃NO₃

Purity: 98.31%

Color and Shape: Solid

Molecular weight: 325.4

Ref: TM-T5512

JNJ16259685

CAS: 409345-29-5

JNJ16259685 is a metabotropic glutamate receptor antagonist that was developed as a potential drug target for the treatment of eye disorders. JNJ16259685 is an experimental model for pharmacological treatment of neuronal death and degeneration, and has been shown to decrease locomotor activity in experimental models. JNJ16259685 binds to the metabotropic glutamate receptor type 1 (mglur1) with high affinity and blocks the binding of glutamate to mglur1, which prevents neuronal death. JNJ16259685 has also been shown to be effective against ryanodine receptor-associated diseases by blocking the release of calcium from intracellular stores.

Formula: C₂₀H₂₃NO₃

Purity: Min. 95%

Molecular weight: 325.4 g/mol

Ref: 3D-JRA34529