CAS 4097-22-7

Dideoxyadenosine

Description:

Dideoxyadenosine, also known as 2',3'-dideoxyadenosine (ddA), is a nucleoside analog that plays a significant role in antiviral therapy, particularly in the treatment of HIV. Its chemical structure is characterized by the absence of hydroxyl groups at the 2' and 3' positions of the ribose sugar, which distinguishes it from the natural nucleoside adenosine. This modification inhibits the action of reverse transcriptase, an enzyme critical for viral replication, thereby preventing the synthesis of viral DNA from RNA. Dideoxyadenosine is typically administered in its phosphate form, which is more biologically active. The compound is soluble in water and exhibits a relatively low toxicity profile, although it can lead to side effects such as mitochondrial toxicity. Its mechanism of action and structural properties make it a valuable tool in molecular biology and pharmacology, particularly in the development of antiretroviral therapies. As a research compound, it is also utilized in various biochemical assays and studies related to nucleic acid metabolism.

Formula: C₁₀H₁₃N₅O₂

InChI: InChI=1S/C10H13N5O2/c11-9-8-10(13-4-12-9)15(5-14-8)7-2-1-6(3-16)17-7/h4-7,16H,1-3H2,(H2,11,12,13)/t6-,7+/m0/s1

InChI key: InChIKey=WVXRAFOPTSTNLL-NKWVEPMBSA-N

SMILES: NC1=C2C(N(C=N2)[C@@H]3O[C@H](CO)CC3)=NC=N1

Synonyms:

• 2,3-Dideoxyadenosine
• Acerola
• Adenosine, 2',3'-dideoxy-
• Adenosine, 2′,3′-dideoxy-
• DDA
• Dideoxyadenosine
• NSC 98700
• Nqz-047
• [5-(6-amino-9H-purin-9-yl)tetrahydrofuran-2-yl]methanol

2',3'-Dideoxyadenosine

CAS: 4097-22-7

Formula: C₁₀H₁₃N₅O₂

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 235.25

Ref: 3B-D3065

2',3'-Dideoxyadenosine, 98%

CAS: 4097-22-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₁₃N₅O₂

Purity: 98%

Molecular weight: 235.24

Ref: 02-J64573

DIDANOSINE IMPURITY G CRS

CAS: 4097-22-7

DIDANOSINE IMPURITY G CRS

Formula: C₁₀H₁₃N₅O₂

Color and Shape: Powder

Molecular weight: 235.2425

Ref: 41-Y0000442

Didanosine Related Compound B (2',3'-dideoxyadenosine)

CAS: 4097-22-7

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₀H₁₃N₅O₂

Color and Shape: Beige Powder

Molecular weight: 235.25 g/mol

Ref: 45-1191237

Adenosine, 2',3'-dideoxy-

CAS: 4097-22-7

Formula: C₁₀H₁₃N₅O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 235.2425

Ref: IN-DA00I80W

2',3'-Dideoxyadenosine

CAS: 4097-22-7

2',3'-Dideoxyadenosine

Purity: 98%

Molecular weight: 289.72g/mol

Ref: 54-BID2035

Dideoxyadenosine

CAS: 4097-22-7

Dideoxyadenosine

Purity: ≥98%

Molecular weight: 235.24g/mol

Ref: 54-BUP06170

2'',3''-Dideoxyadenosine

CAS: 4097-22-7

Formula: C₁₀H₁₃N₅O₂

Purity: ≥ 98.0%

Color and Shape: White to almost white powder

Molecular weight: 235.24

Ref: 7W-GE2863

Dideoxyadenosine

CAS: 4097-22-7

2',3'-Dideoxyadenosine is an inhibitor of HIV replication with antiretroviral activity and antiviral efficacy [1].

Formula: C₁₀H₁₃N₅O₂

Purity: 99.28%

Color and Shape: Physical Description Off-White Powder (Ntp 1992)

Molecular weight: 235.24

Ref: TM-T5949

9-(2,3-Dideoxy-β-D-glycero-pentofuranosyl)-9H-purin-6-amine (2',3'-Dideoxyadenosine)

Controlled Product

CAS: 4097-22-7

Formula: C₁₀H₁₃N₅O₂

Color and Shape: Neat

Molecular weight: 235.243

Ref: 86-MM1047.02

2',3'-Dideoxyadenosine

CAS: 4097-22-7

2',3'-Dideoxyadenosine is a nucleoside analog that inhibits HIV replication and is a competitive inhibitor of adenylyl cyclase. This latter action reduces levels of cyclic adenosine monophosphate (cAMP)

Formula: C₁₀H₁₃N₅O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 235.25 g/mol

Ref: 3D-ND06741

((2S,5R)-5-(6-Amino-9H-purin-9-yl)tetrahydrofuran-2-yl)methanol

CAS: 4097-22-7

Formula: C₁₀H₁₃N₅O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 235.247

Ref: 10-F211575

2,3-Dideoxyadenosine (ddA) extrapure, 98%

CAS: 4097-22-7

Formula: C₁₀H₁₃N₅O₂

Molecular weight: 235.25

Ref: SR-95525

Dideoxy Adenosine

Controlled Product

CAS: 4097-22-7

Formula: C₁₀H₁₃N₅O₂

Color and Shape: Neat

Molecular weight: 235.243

Ref: TR-D439850

Didanosine EP Impurity G

CAS: 4097-22-7

Formula: C₁₀H₁₃N₅O₂

Molecular weight: 235.25

Ref: ST-EA-CP-D114007