CAS 4097-22-7: Dideoxyadenosine
Description:Dideoxyadenosine, also known as 2',3'-dideoxyadenosine (ddA), is a nucleoside analog that plays a significant role in antiviral therapy, particularly in the treatment of HIV. Its chemical structure is characterized by the absence of hydroxyl groups at the 2' and 3' positions of the ribose sugar, which distinguishes it from the natural nucleoside adenosine. This modification inhibits the action of reverse transcriptase, an enzyme critical for viral replication, thereby preventing the synthesis of viral DNA from RNA. Dideoxyadenosine is typically administered in its phosphate form, which is more biologically active. The compound is soluble in water and exhibits a relatively low toxicity profile, although it can lead to side effects such as mitochondrial toxicity. Its mechanism of action and structural properties make it a valuable tool in molecular biology and pharmacology, particularly in the development of antiretroviral therapies. As a research compound, it is also utilized in various biochemical assays and studies related to nucleic acid metabolism.
Formula:C10H13N5O2
InChI:InChI=1S/C10H13N5O2/c11-9-8-10(13-4-12-9)15(5-14-8)7-2-1-6(3-16)17-7/h4-7,16H,1-3H2,(H2,11,12,13)/t6-,7+/m0/s1
InChI key:InChIKey=WVXRAFOPTSTNLL-NKWVEPMBSA-N
SMILES:OCC1OC(N2C=NC=3C(=NC=NC32)N)CC1
- Synonyms:
- 2,3-Dideoxyadenosine
- Acerola
- Adenosine, 2',3'-dideoxy-
- Adenosine, 2′,3′-dideoxy-
- DDA
- Dideoxyadenosine
- NSC 98700
- Nqz-047
- [5-(6-amino-9H-purin-9-yl)tetrahydrofuran-2-yl]methanol

2',3'-Dideoxyadenosine
Ref: 3B-D3065
100mg | 329.00 € |

2',3'-Dideoxyadenosine, 98%
Ref: 02-J64573
25mg | To inquire |

Didanosine impurity G CRS
Ref: 41-Y0000442
10mg | 115.00 € |

Didanosine Related Compound B (2',3'-dideoxyadenosine)
Ref: 45-1191237
25mg | 775.00 € |

Adenosine, 2',3'-dideoxy-
- 5-membered Heterocycles
- Furan
- Tetrahydrofuran
- 6-membered Heterocycles
- See more categories
- Glycoscience
- Antivirals
- Nucleotides
- Nucleosides
- APIs for research and impurities
- Pyrimidine
- Biochemicals and Reagents
- Cellular and Molecular Biology
- Antibiotics
- Salts and Derivatives of Active Pharmaceutical Ingredients (API)
Ref: IN-DA00I80W
1g | 194.00 € | ||
5g | To inquire | ||
5mg | 44.00 € | ||
25mg | 62.00 € | ||
100mg | 98.00 € | ||
250mg | 135.00 € |

2'',3''-Dideoxyadenosine
Ref: 7W-GE2863
25mg | 175.00 € |

Ref: 54-BID2035
1g | 282.00 € | ||
5g | 933.00 € | ||
100mg | 72.00 € | ||
250mg | 122.00 € |

Ref: 54-BUP06170
25mg | 171.00 € | ||
50mg | 234.00 € | ||
100mg | 338.00 € |

9-(2,3-Dideoxy-β-D-glycero-pentofuranosyl)-9H-purin-6-amine (2',3'-Dideoxyadenosine)
Controlled ProductRef: 86-MM1047.02-0025
25mg | 622.00 € | ||
4x25mg | To inquire |

((2S,5R)-5-(6-Amino-9H-purin-9-yl)tetrahydrofuran-2-yl)methanol
Ref: 10-F211575
1g | 227.00 € | ||
5g | 765.00 € | ||
100mg | 60.00 € | ||
250mg | 94.00 € |

Dideoxyadenosine
Ref: TM-T5949
5mg | 47.00 € | ||
10mg | 70.00 € | ||
25mg | 103.00 € | ||
50mg | 150.00 € | ||
100mg | 217.00 € | ||
1mL*10mM (DMSO) | 77.00 € |

9-(2,3-Dideoxy-β-D-glycero-pentofuranosyl)-9H-purin-6-amine (2',3'-Dideoxyadenosine)
Controlled ProductRef: 86-MM1047.02
25mg | 622.00 € | ||
4x25mg | To inquire |

2',3'-Dideoxyadenosine
Ref: 3D-ND06741
1g | 1,053.00 € | ||
2g | 1,558.00 € | ||
100mg | 233.00 € | ||
250mg | 470.00 € | ||
500mg | 639.00 € |

Ref: SR-95525
5mg | 45.00 € |

Dideoxy Adenosine
Controlled ProductRef: TR-D439850
2500mg | 5,796.00 € |