CAS 4098-40-2

(-)-Mitragynine

Description:

(-)-Mitragynine is an indole alkaloid primarily found in the leaves of the Mitragyna speciosa tree, commonly known as kratom. This compound exhibits a complex pharmacological profile, acting as both a stimulant and a sedative depending on the dosage. At lower doses, it may enhance energy and alertness, while higher doses can produce sedative effects and analgesia. The substance interacts with various neurotransmitter systems, particularly the opioid receptors, which contributes to its pain-relieving properties. (-)-Mitragynine is also noted for its potential to influence mood and anxiety levels. Its chemical structure features a unique indole framework, which is characteristic of many alkaloids. Despite its traditional use in Southeast Asia for medicinal and recreational purposes, (-)-Mitragynine has garnered attention for its safety profile and potential for abuse, leading to ongoing research and regulatory scrutiny in various countries. As with any psychoactive substance, the effects can vary significantly among individuals, and caution is advised regarding its use.

Formula: C₂₃H₃₀N₂O₄

InChI: InChI=1S/C23H30N2O4/c1-5-14-12-25-10-9-15-21-18(7-6-8-20(21)28-3)24-22(15)19(25)11-16(14)17(13-27-2)23(26)29-4/h6-8,13-14,16,19,24H,5,9-12H2,1-4H3/b17-13+/t14-,16+,19+/m1/s1

InChI key: InChIKey=LELBFTMXCIIKKX-QVRQZEMUSA-N

SMILES: O(C)C1=C2C3=C([C@]4(N(CC3)C[C@@H](CC)[C@@H](\C(\C(OC)=O)=C/OC)C4)[H])NC2=CC=C1

Synonyms:

• (-)-Mitragynine
• (16E,20b)-16,17-Didehydro-9,17-dimethoxycorynan-16-carboxylic Acid Methyl Ester
• 4098-40-2
• 9-Methoxycorynantheidine
• Corynan-16-carboxylic acid, 16,17-didehydro-9,17-dimethoxy-, methyl ester, (16E,20.beta.)-
• Corynan-16-carboxylic acid, 16,17-didehydro-9,17-dimethoxy-, methyl ester, (16E,20β)-
• Corynantheidine, 9-methoxy-
• Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethyl-1,2,3,4,6,7,12,12b-octahydro-8-methoxy-α-(methoxymethylene)-, methyl ester, (αE,2S,3S,12bS)-
• Indolo[2,3-a]quinolizine-2-acetic acid, 3-ethyl-1,2,3,4,6,7,12,12b-octahydro-8-methoxy-α-(methoxymethylene)-, methyl ester, [2S-[2α(E),3α,12bβ]]-
• Methyl (16E,20beta)-9,17-dimethoxycoryn-16-en-16-carboxylate
• Methyl (16E,20beta)-9-methoxy-16-(methoxymethylene)corynan-17-oate
• Mitragynin

Mitragynine, 0.1mg/ml in Methanol

CAS: 4098-40-2

Color and Shape: Colourless

Ref: LP-MTR-1610-0.1LM

Mitragynine, 1mg/ml in Methanol

CAS: 4098-40-2

Color and Shape: Colourless

Ref: LP-MTR-1610-1LM

Mitragynine

CAS: 4098-40-2

Color and Shape: Neat

Ref: LP-MTR-1610-10

Mitragynine

CAS: 4098-40-2

Formula: C₂₃H₃₀N₂O₄

Color and Shape: Brown Solid

Molecular weight: 398.50

Ref: 4Z-M-186001

Mitragynine 100 µg/mL in Methanol

Controlled Product

CAS: 4098-40-2

Formula: C₂₃H₃₀N₂O₄

Color and Shape: Single Solution

Molecular weight: 398.50

Ref: 04-A15273200ME-100

Mitragynine-13C-d3

CAS: 4098-40-2

Formula: CC₂₂H₂₇D₃N₂O₄

Molecular weight: 402.51

Ref: 4Z-M-186003

Mitragynine

CAS: 4098-40-2

Applications Mitragynine is a neurochemical, having both stimulant and opiate-like effects depending on the dosage. Currently, Mitragynine is being investigated for its ability to treat hard drug addiction.
References Kikura-Hanajiri, R., et al.: For. Toxicol., 27, 67 (2009); Bjoernstad, K., et al.: Clin. Toxicol., 47, 566 (2009); Parthasarathy, S., et al.: Anal. Bioanal. Chem., 397, 2023 (2010);

Formula: C₂₃H₃₀N₂O₄

Color and Shape: Neat

Molecular weight: 398.50

Ref: TR-M373550

Mitragynine (100 ug/mL in Methanol)

CAS: 4098-40-2

Formula: C₂₃H₃₀N₂O₄

Color and Shape: Single Solution

Molecular weight: 398.50

Ref: TR-KIT0290

Mitragynine - 95%

Controlled Product

CAS: 4098-40-2

An indole alkaloid from tropical plant Mitragyna speciosa with psychostimulatory and opioid-like effects. It agonizes μ- and δ-opioid receptors and has anti-nociceptive properties. At low doses, the compound is stimulant but at high doses, it exerts sedative effects. It has been shown to induce conditioned place preference (CPP) in mice, indicating its role in reward and motivation pathways. Moreover, it has addiction potential with cognitive impairments.

Formula: C₂₃H₃₀N₂O₄

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 398.5 g/mol

Ref: 3D-BM164595

Mitragynine - 97%

Controlled Product

CAS: 4098-40-2

An indole alkaloid from tropical plant Mitragyna speciosa with psychostimulatory and opioid-like effects. It agonizes μ- and δ-opioid receptors and has anti-nociceptive properties. At low doses, the compound is stimulant but at high doses, it exerts sedative effects. It has been shown to induce conditioned place preference (CPP) in mice, indicating its role in reward and motivation pathways. Moreover, it has addiction potential with cognitive impairments.

Formula: C₂₃H₃₀N₂O₄

Purity: Min. 97 Area-%

Color and Shape: Powder

Molecular weight: 398.5 g/mol

Ref: 3D-FM26024