CAS 4099-84-7

2-amino-9-(5-amino-5-deoxypentofuranosyl)-3,9-dihydro-6H-purin-6-one

Description:

2-amino-9-(5-amino-5-deoxypentofuranosyl)-3,9-dihydro-6H-purin-6-one, commonly known as a derivative of purine, is a nucleoside analog that features both amino and deoxypentofuranosyl components. This compound is characterized by its purine base structure, which includes a fused imidazole and pyrimidine ring system, contributing to its biological activity. The presence of amino groups enhances its potential for hydrogen bonding and interaction with biological macromolecules, such as nucleic acids. This compound is often studied for its role in nucleic acid metabolism and potential therapeutic applications, particularly in antiviral and anticancer research. Its solubility and stability in various solvents can vary, influencing its bioavailability and efficacy in biological systems. The CAS number 4099-84-7 uniquely identifies this substance, facilitating its recognition in scientific literature and databases. Overall, this compound exemplifies the complexity and diversity of nucleoside analogs in medicinal chemistry.

Formula: C₁₀H₁₄N₆O₄

InChI: InChI=1/C10H14N6O4/c11-1-3-5(17)6(18)9(20-3)16-2-13-4-7(16)14-10(12)15-8(4)19/h2-3,5-6,9,17-18H,1,11H2,(H3,12,14,15,19)

SMILES: C(C1C(C(C(n2cnc3c2[nH]c(=N)nc3O)O1)O)O)N

Synonyms:

• 2H-purin-6-ol, 9-(5-amino-5-deoxypentofuranosyl)-3,9-dihydro-2-imino-

Guanosine, 5'-amino-5'-deoxy-

CAS: 4099-84-7

Formula: C₁₀H₁₄N₆O₄

Purity: 95%

Color and Shape: Solid

Molecular weight: 282.2560

Ref: IN-DA01DQB8

5'-Amino-5'-deoxyguanosine

CAS: 4099-84-7

5'-Amino-5'-deoxyguanosine

Purity: 95%

Molecular weight: 282.26g/mol

Ref: 54-OR1006744

5''-Amino-5''-deoxyguanosine

CAS: 4099-84-7

Formula: C₁₀H₁₄N₆O₄

Purity: (HPLC) ≥ 90.0%

Color and Shape: White to off-white solid

Molecular weight: 282.26

Ref: 7W-GN3747

5'-Amino-5'-deoxyguanosine

CAS: 4099-84-7

5'-Amino-5'-deoxyguanosine (5-ADG) is an intermediate in the de novo synthesis of guanine nucleotides. It can be synthesized from 5-aminoimidazole ribonucleotide and guanosine monophosphate (GMP). 5-ADG is a substrate for the enzyme GTP cyclohydrolase, which converts it to GMP. This intermediate can also be formed by the action of phosphoryl chloride on 5-aminoimidazole ribonucleotide. The reaction of 5-ADG with malonic acid leads to the formation of inosinic acid, which has been postulated to be a precursor of purines. This conversion is catalyzed by adenylosuccinate synthetase and the enzyme adenylosuccinase.

Formula: C₁₀H₁₄N₆O₄

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 282.26 g/mol

Ref: 3D-NA16031

2-amino-9-[(2R,3R,4S,5R)-5-(aminomethyl)-3,4-dihydroxyoxolan-2-yl]-6,9-dihydro-3H-purin-6-one

CAS: 4099-84-7

Purity: 95%

Color and Shape: Solid

Molecular weight: 282.2600098

Ref: 10-F611611