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CAS 410074-74-7

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Amitifadine hydrochloride

Description:
Amitifadine hydrochloride is a chemical compound primarily studied for its potential use in treating depression and other mood disorders. It is classified as a novel antidepressant and is known for its unique mechanism of action, which involves the modulation of neurotransmitter systems, particularly serotonin, norepinephrine, and dopamine. The compound is characterized by its hydrochloride salt form, which enhances its solubility and stability in aqueous solutions, making it suitable for pharmaceutical applications. Amitifadine has shown promise in preclinical and clinical studies, demonstrating efficacy in alleviating depressive symptoms with a potentially favorable side effect profile compared to traditional antidepressants. Its pharmacokinetics, including absorption, distribution, metabolism, and excretion, are critical for determining its therapeutic potential and safety. As research continues, the understanding of its full range of effects and optimal dosing regimens will be essential for its development as a therapeutic agent.
Formula:C11H11Cl2N·ClH
InChI:InChI=1S/C11H11Cl2N.ClH/c12-9-2-1-7(3-10(9)13)11-4-8(11)5-14-6-11;/h1-3,8,14H,4-6H2;1H/t8-,11+;/m1./s1
InChI key:InChIKey=KAGBHVBIOJBGBD-NINOIYOQSA-N
SMILES:ClC=1C=C([C@]23[C@](C2)(CNC3)[H])C=CC1Cl.Cl
Synonyms:
  • 3-Azabicyclo[3.1.0]hexane, 1-(3,4-dichlorophenyl)-, hydrochloride (1:1), (1R,5S)-
  • Amitifadine hydrochloride
  • DOV 21947 hydrochloride
  • EB 1010 hydrochloride
  • 3-Azabicyclo[3.1.0]hexane, 1-(3,4-dichlorophenyl)-, hydrochloride, (1R,5S)-
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