CAS 410074-75-8

(-)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane

Description:

(-)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane, with CAS number 410074-75-8, is a bicyclic compound characterized by its unique azabicyclo structure, which incorporates a nitrogen atom into a bicyclic framework. This compound features a dichlorophenyl group, indicating the presence of two chlorine atoms on a phenyl ring, which can significantly influence its chemical reactivity and biological activity. The stereochemistry of the compound is denoted by the prefix "(-)", indicating that it is the enantiomer with specific optical activity. Such compounds often exhibit interesting pharmacological properties, making them of interest in medicinal chemistry. The bicyclic structure can contribute to its ability to interact with biological targets, potentially affecting neurotransmitter systems. Additionally, the presence of chlorine substituents can enhance lipophilicity and modulate the compound's interaction with cellular membranes. Overall, this compound's unique structural features suggest potential applications in drug development and research into its biological effects.

Formula: C₁₁H₁₁Cl₂N

InChI: InChI=1S/C11H11Cl2N/c12-9-2-1-7(3-10(9)13)11-4-8(11)5-14-6-11/h1-3,8,14H,4-6H2/t8-,11+/m0/s1

InChI key: InChIKey=BSMNRYCSBFHEMQ-GZMMTYOYSA-N

SMILES: ClC=1C=C([C@@]23[C@@](C2)(CNC3)[H])C=CC1Cl

Synonyms:

• (1S,5R)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane
• 3-Azabicyclo[3.1.0]hexane, 1-(3,4-dichlorophenyl)-, (1S,5R)-
• DOV 102677
• (-)-1-(3,4-Dichlorophenyl)-3-azabicyclo[3.1.0]hexane

DOV-102677

CAS: 410074-75-8

Merck's DOV-102677, a triple reuptake inhibitor in trials, is the enantiomer of DOV-216,303.

Formula: C₁₁H₁₁Cl₂N

Color and Shape: Solid

Molecular weight: 228.12

Ref: TM-T69275